dilithio-1,3-bis(fluorenyl)propane | 172365-87-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: dilithio-1,3-bis(fluorenyl)propane
• CAS: 172365-87-6
• 化学式: C₂₉H₂₂Li₂
• 分子量: 384.376
• InChiKey: PRWPEZRPWZSOBT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.34
• 重原子数：
  31.0
• 可旋转键数：
  4.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  dilithio-1,3-bis(fluorenyl)propane 在 四氯化钛 作用下， 以 正戊烷 为溶剂， 反应 48.0h， 以23%的产率得到1,2,3,4,7,8,9,10-tetrabenzodispiro<4.0.4.3>trideca-1,3,7,9-tetraene
  参考文献：
  名称：

  Formation of tetrabenzodispiro[4.0.4.3]tridecatetraene by a titanium mediated fluorenyl coupling reaction

  摘要：

  Treatment of 1,3-propanediol-ditosylate with fluorenyllithium yields 1,3-bis(fluorenyl)propane (5). Subsequent addition of methyllithium gives the corresponding dilithio compound 6. Dilithio-1,3-bis(fluorenyl)propane (6) was treated with titanium tetrachloride to yield the organic tetrabenzodispiro[4.0.4.3]tridecatetraene product 7, presumably formed by means of a carbon-carbon coupling reaction involving substituted fluorenyl radicals. The organic compounds 5 and 7 were identified by X-ray crystal structure analyses.

  DOI：

  10.1016/0022-328x(95)05588-g
• 作为产物：
  描述：

  1,3-bis(fluorenyl)propane 在 甲基锂 作用下， 以 乙醚 为溶剂， 以98%的产率得到dilithio-1,3-bis(fluorenyl)propane
  参考文献：
  名称：

  Formation of tetrabenzodispiro[4.0.4.3]tridecatetraene by a titanium mediated fluorenyl coupling reaction

  摘要：

  Treatment of 1,3-propanediol-ditosylate with fluorenyllithium yields 1,3-bis(fluorenyl)propane (5). Subsequent addition of methyllithium gives the corresponding dilithio compound 6. Dilithio-1,3-bis(fluorenyl)propane (6) was treated with titanium tetrachloride to yield the organic tetrabenzodispiro[4.0.4.3]tridecatetraene product 7, presumably formed by means of a carbon-carbon coupling reaction involving substituted fluorenyl radicals. The organic compounds 5 and 7 were identified by X-ray crystal structure analyses.

  DOI：

  10.1016/0022-328x(95)05588-g