Phenyl-β-aethoxy-propionat | 27850-45-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: Phenyl-β-aethoxy-propionat
• 英文别名: Phenyl 3-ethoxypropanoate
• CAS: 27850-45-9
• 化学式: C₁₁H₁₄O₃
• 分子量: 194.23
• InChiKey: PEXWPUATZOMEFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-乙氧基丙酸 、 苯酚 在 三氟乙酸酐 作用下， 生成 Phenyl-β-aethoxy-propionat
  参考文献：
  名称：

  Aminolysis of esters. IX. Nature of transition states in the aminolysis of phenyl acetates

  摘要：

  DOI：

  10.1021/ja00708a044

文献信息

• [EN] NOVEL SALTS, CRYSTALLINE FORMS AND PREMIX OF HYPOLIPIDEMIC AGENT<br/>[FR] NOUVEAUX SELS, FORMES CRISTALLINES ET PRÉMÉLANGE D'AGENT HYPOLIPIDÉMIQUE
  申请人：CADILA HEALTHCARE LTD

  公开号：WO2020183379A1

  公开（公告）日：2020-09-17

  Present invention relates to novel salts of saroglitazar and certain polymorphic forms of saroglitazar salts. Invention provides process for the preparation of novel salts and polymorphic forms of saroglitazar. Invention also provides novel co-precipitants or premixes of saroglitazar with pharmaceutically acceptable excipients/secondary therapeutic agent and process for the preparing same.

  本发明涉及萨罗格利他新型盐和某些萨罗格利他盐的多晶形式。本发明提供了制备新型盐和多晶形式的方法。本发明还提供了萨罗格利他与药学上可接受的辅料/次级治疗剂的新型共沉淀剂或预混合物，以及其制备方法。
• [EN] SYNERGISTIC COMPOSITIONS<br/>[FR] COMPOSITIONS SYNERGIQUES
  申请人：CADILA HEALTHCARE LTD

  公开号：WO2015001573A9

  公开（公告）日：2016-02-25
• SYNERGISTIC COMPOSITIONS
  申请人：Cadila Healthcare Limited

  公开号：EP3016650A1

  公开（公告）日：2016-05-11
• MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR
  申请人：XIAMEN SINOPEG BIOTECH CO., LTD.

  公开号：US20170312363A1

  公开（公告）日：2017-11-02

  Disclosed are a multifunctionalized polyethylene glycol derivative and a preparation method therefor. The derivative has an H-shaped structure as represented by formula (1) and comprises one linear core LPEG and four PEG branch chains, where n 1 , n 2 , n 3 , and n 4 respectively are the degrees of polymerization of the branch chains, U 1 and U 2 are trivalent branching groups connecting the core LPEG to two of the PEG branch chains, F 1 and F 2 contain a functional group or a protected form R 01 thereof and may or may not contain a branched group G, correspondingly, the number of R 01 is one or more, F 1 and F 2 are either identical or different, any one linking group in the molecule or any linking group formed with an adjacent heteroatom group can either remain stable or be degraded, and any one PEG segment in the molecule is discretely polydispersed or monodispersed. The multifunctional polyethylene glycol is flexible and diverse in terms of branch structures and the lengths of branching arms, has various parameters and performance indicators that are adjustable and easy to control, and has a broad applicability.
• [EN] THE TREATMENT OF COGNITIVE AND PSYCHOTIC DISORDERS<br/>[FR] TRAITEMENT DE TROUBLES COGNITIFS ET PSYCHOTIQUES
  申请人：CAMBRIDGE ENTPR LTD

  公开号：WO2007083146A2

  公开（公告）日：2007-07-26

  [EN] An anti-diabetic agent such as insulin is useful for the treatment of a psychotic disorder such as a schizophrenic disorder.
  [FR] Cette invention concerne l'utilisation d'un agent antidiabétique tel que l'insuline pour traiter un trouble psychotique tel qu'un trouble schizophrénique.