| 1195987-59-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• CAS: 1195987-59-7
• 化学式: C₃₂H₂₆N₄OS₂
• 分子量: 546.717
• InChiKey: LESQYXYRUPXVMV-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  甲氧苯胺 、 丙二腈 、 1-Benzyl-3.5-di-<2-thenyliden>-4-piperidon 在 溶剂黄146 作用下， 反应 0.1h， 以91%的产率得到
  参考文献：
  名称：

  Diversity Synthesis of N-Substituted 2-Amino-1,6-naphthyridine Derivatives under Microwave Irradiation

  摘要：

  A sequential three-component reaction of 3,5-diarylidenepiperidin-4-one, malononitrile, and amine (such as aromatic amine, cyclopropanamine, and NH4OAc) in acetic acid under microwave irradiation has been developed. In this one-pot reaction, a series of new N-substituted 2-amino-1,6-naphthyridine derivatives were synthesized with excellent yields. This method has the advantages of operational simplicity and increased safety for small-scale fast synthesis of N-aryl 2-amino-1,6-naphthyridines for biomedical screening.

  DOI：

  10.1021/cc900030e