2-Benzyl-1,3-dioxocane | 1423022-02-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二恶烷
• 英文名称: 2-Benzyl-1,3-dioxocane
• CAS: 1423022-02-9
• 化学式: C₁₃H₁₈O₂
• 分子量: 206.285
• InChiKey: RCUBZNYYVQLKTN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,5-戊二醇 、 苯乙醛 在 sulfonic acid-functionalized mesoporous chromium (III)terephthalate 作用下， 以 环己烷 为溶剂， 反应 5.0h， 以41.6%的产率得到2-Benzyl-1,3-dioxocane
  参考文献：
  名称：

  Synthesis of sulfonic acid-functionalized MIL-101 for acetalization of aldehydes with diols

  摘要：

  A metal-organic framework (MOF) MIL-101 bearing sulfonic acid groups (SO3 H-MIL-101), was prepared through one-pot hydrothermal synthesis strategy. This MOF was systemically characterized via XRD, N-2 adsorption, acid-base titration, XPS, FT-IR techniques, and elemental analysis, and then used as a heterogeneous catalyst for liquid-phase acetalizations of various aldehydes with diols. The obtained SO3H-MIL-101 shows high catalytic activity in the acetalizations due to the high utilization efficiency of its functionalized acid sites. Additionally, this catalyst can be easily recovered and reused five times in succession without significant loss of catalytic activity. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2013.12.005

文献信息

• [EN] FLAVONOID PPAR AGONISTS<br/>[FR] AGONISTES FLAVONOÏDES DE PPAR
  申请人：UNIV SYDNEY

  公开号：WO2009026657A1

  公开（公告）日：2009-03-05

  The present invention relates to PPAR agonists, and their use in therapy including the treatment of disease. In particular, the invention relates to flavonoid compounds which are PPAR-gamma agonists and/or PPAR alpha/gamma dual agonists.