2-bromo-6-chlorohydroquinone | 150900-92-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-bromo-6-chlorohydroquinone
• 英文别名: 2-Brom-6-chlor-hydrochinon；2-Bromo-6-chlorobenzene-1,4-diol；2-bromo-6-chlorobenzene-1,4-diol
• CAS: 150900-92-8
• 化学式: C₆H₄BrClO₂
• 分子量: 223.454
• InChiKey: BICQALILHYFMQG-UHFFFAOYSA-N

物化性质

• 沸点：
  279.4±35.0 °C(Predicted)
• 密度：
  1.952±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-bromo-6-chlorohydroquinone 生成 2-bromo-6-chloro-benzoquinone
  参考文献：
  名称：

  Molecular Characterization in the VP7, VP4 and NSP4 Genes of Human Rotavirus Serotype 4 (G4) Isolated in Japan and Kenya

  摘要：

  AbstractThe VP7, VP4 and NSP4 genes of human rotavirus serotype 4 (G4) were analyzed to investigate intraserotypic variations. The techniques used included reverse transcription polymerase chain reaction with subtype specific primers, restriction fragment length polymorphism analysis and sequence analysis. Twelve isolates (nine from Japan and three from Kenya) and two standard strains (Hochi, Odelia) were G4A P[8] Wa group NSP4. A standard strain (ST3) was G4A P[6] Wa group NSP4 and a strain (VA70) was G4B P[8] Wa group NSP4. These results show G4 rotaviruses can be divided into three combinations at the moment.

  DOI：

  10.1111/j.1348-0421.2001.tb01286.x
• 作为产物：
  描述：

  2,4,4-tribromo-6-chloro-cyclohexa-2,5-dienone 在 硝酸 、 亚硫酸 作用下， 生成 2-bromo-6-chlorohydroquinone
  参考文献：
  名称：

  Kohn; Sussmann, Monatshefte fur Chemie, 1927, vol. 48, p. 209

  摘要：

  DOI：

文献信息

• <i>E</i>-Dakin reaction: oxidation of hydroxybenzaldehydes to phenols with electrochemically generated peroxodicarbonate as sustainable <i>ex-cell</i> oxidizer
  作者：Fiona Sprang、Niclas Schupp、Philipp J. Kohlpaintner、Lukas J. Gooßen、Siegfried R. Waldvogel

  DOI：10.1039/d3gc04597h

  日期：——

  Electrochemically generated peroxodicarbonate solution efficiently oxidizes hydroxybenzaldehydes to valuable phenols. The reaction is carried out in aqueous media without additional solvents or additives. The reaction gives high yields of up to 97% and tolerates a broad variety of substituents, as demonstrated by 20 diverse examples. It was successfully scaled to multi-gram range. This transformation

  电化学产生的过氧化二碳酸盐溶液可有效地将羟基苯甲醛氧化为有价值的酚类。该反应在水介质中进行，无需额外的溶剂或添加剂。正如 20 个不同的例子所证明的那样，该反应的产率高达 97%，并且可以耐受多种取代基。它已成功扩展到数克范围。这一转变进一步扩大了绿色氧化剂过氧化二碳酸酯的合成适用性，它可以根据需要从生态安全的碳酸盐溶液中生成，并且在弱碱性条件下具有高氧化电位。
• Kohn; Sussmann, Monatshefte fur Chemie, 1927, vol. 48, p. 209
  作者：Kohn、Sussmann

  DOI：——

  日期：——
• Molecular Characterization in the VP7, VP4 and NSP4 Genes of Human Rotavirus Serotype 4 (G4) Isolated in Japan and Kenya
  作者：Satoshi Kudo、Yumei Zhou、Xin-Ru Cao、Shigeki Yamanishi、Shuji Nakata、Hiroshi Ushijima

  DOI：10.1111/j.1348-0421.2001.tb01286.x

  日期：2001.2

  AbstractThe VP7, VP4 and NSP4 genes of human rotavirus serotype 4 (G4) were analyzed to investigate intraserotypic variations. The techniques used included reverse transcription polymerase chain reaction with subtype specific primers, restriction fragment length polymorphism analysis and sequence analysis. Twelve isolates (nine from Japan and three from Kenya) and two standard strains (Hochi, Odelia) were G4A P[8] Wa group NSP4. A standard strain (ST3) was G4A P[6] Wa group NSP4 and a strain (VA70) was G4B P[8] Wa group NSP4. These results show G4 rotaviruses can be divided into three combinations at the moment.