TeMF | 1370417-46-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: TeMF
• 英文别名: 4-methyl-2-[(4-oxo-2,3-dihydro-1H-naphthalen-1-yl)oxy]-2H-furan-5-one
• CAS: 1370417-46-1
• 化学式: C₁₅H₁₄O₄
• 分子量: 258.274
• InChiKey: IWDRCLROIYMZHH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• NOVEL COMPOUND HAVING STRIGOLACTONE-LIKE ACTIVITY AND USE THEREOF
  申请人：Riken

  公开号：EP2623502A1

  公开（公告）日：2013-08-07

  The present invention provides a compound that has an activity equal to or higher than that of natural strigolactone, can be chemically synthesized by a convenient step and at low cost, exhibits stability in environments, and has no or weak seed germination-promoting effect on plants of the genus Striga or Orobanche. Specifically, the present invention provides a compound represented by the general formula (III) or a salt thereof, wherein X represents a lower alkyl group or the like; Q represents a single bond or the like; and ring C represents a 6-membered ring represented by the formula (IVa) or the like wherein R1, R2, R3, and R4 each independently represent a carbon atom or the like, Z1 and Z2 are bonded to the ring atoms of ring C and each independently represent a hydrogen atom, a halogen atom, or the like, and the groups R5, R6, R7, Z3, Z4, and Z5 are as defined in the specification.

  本发明提供了一种化合物，其活性等同于或高于天然绞股蓝内酯，可通过简便的步骤以较低的成本化学合成，在环境中表现出稳定性，且对绞股蓝属或鄂伦春属植物无促进种子萌发作用或促进作用较弱。具体而言，本发明提供了通式（III）代表的化合物或其盐，其中 X 代表低级烷基或类似物；Q 代表单键或类似物；其中 R1、R2、R3 和 R4 各自独立地代表碳原子或类似物，Z1 和 Z2 与环 C 的环原子键合，各自独立地代表氢原子、卤素原子或类似物，基团 R5、R6、R7、Z3、Z4 和 Z5 如说明书中所定义。