(±)-1,5-dibenzyl-4,8-dicyclohexyl-1,5-diazocane-2,6-dione | 1415922-38-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酰胺类
• 英文名称: (±)-1,5-dibenzyl-4,8-dicyclohexyl-1,5-diazocane-2,6-dione
• CAS: 1415922-38-1
• 化学式: C₃₂H₄₂N₂O₂
• 分子量: 486.698
• InChiKey: ISACFISGKTVLOX-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  3-benzylamino-3-cyclohexyl-propionic acid 在 苯膦酰二氯 、 三乙胺 作用下， 以 苯 为溶剂， 反应 0.5h， 以72%的产率得到(±)-1-benzyl-4-cyclohexylazetidin-2-one
  参考文献：
  名称：

  Microwave-Assisted Synthesis ofβ-Lactams and Cyclo-β-dipeptides

  摘要：

  AbstractDifferent cyclo‐β‐dipeptides were prepared from corresponding N‐substituted β‐alanine derivatives under mild conditions using PhPOCl2 as activating agent in benzene and Et3N as base. To evaluate β3‐substituent influence, the amino acids 7–26 were synthesized, and a β‐lactam formation reaction was carried out instead of cyclo‐β‐dipeptide formation. The crystal structures of three derivatives of cyclo‐β‐peptides and one β‐lactam are presented.

  DOI：

  10.1002/hlca.201200449