N-(4-ethynylphenyl)-2,5,8,11,14,17-hexaoxabicyclo[16.4.0]docosa-1(18),19,21-triene-20-carboxamide | 1612796-67-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-ethynylphenyl)-2,5,8,11,14,17-hexaoxabicyclo[16.4.0]docosa-1(18),19,21-triene-20-carboxamide
• CAS: 1612796-67-4
• 化学式: C₂₅H₂₉NO₇
• 分子量: 455.508
• InChiKey: NMPDIZIVEULWRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  33
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  84.5
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  顺-二氯双(三乙基膦)铂(II) 、 N-(4-ethynylphenyl)-2,5,8,11,14,17-hexaoxabicyclo[16.4.0]docosa-1(18),19,21-triene-20-carboxamide 在 copper(l) iodide 、 二异丙胺 作用下， 以 氯仿 为溶剂， 反应 72.0h， 以83%的产率得到
  参考文献：
  名称：

  Cooperative Complexation of Amino Acid Derivatives to Platinum Acetylide-Based Bolaamphiphile

  摘要：

  A platinum(II) acetylide-based bolaamphiphile equipped with two peripheral B18C6 moieties has been successfully prepared, which demonstrates cooperative recognition behavior toward l-alanine ester salt in chloroform. In a polar methanol/chloroform (3/1, v/v) medium, the amino acid additives influence the aggregation of the bolaamphiphile significantly, leading to the morphological transition from nanospherical to disordered structures. The adaptive properties of the current host-guest binary system will benefit the development of stimuli-responsive supramolecular materials.

  DOI：

  10.1021/ol500752b
• 作为产物：
  描述：

  4'-羧基苯并-18-冠6-醚 、 4-乙炔基苯胺 在 4-二甲氨基吡啶 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 48.0h， 以79%的产率得到N-(4-ethynylphenyl)-2,5,8,11,14,17-hexaoxabicyclo[16.4.0]docosa-1(18),19,21-triene-20-carboxamide
  参考文献：
  名称：

  Cooperative Complexation of Amino Acid Derivatives to Platinum Acetylide-Based Bolaamphiphile

  摘要：

  A platinum(II) acetylide-based bolaamphiphile equipped with two peripheral B18C6 moieties has been successfully prepared, which demonstrates cooperative recognition behavior toward l-alanine ester salt in chloroform. In a polar methanol/chloroform (3/1, v/v) medium, the amino acid additives influence the aggregation of the bolaamphiphile significantly, leading to the morphological transition from nanospherical to disordered structures. The adaptive properties of the current host-guest binary system will benefit the development of stimuli-responsive supramolecular materials.

  DOI：

  10.1021/ol500752b

文献信息

• Cooperative Complexation of Amino Acid Derivatives to Platinum Acetylide-Based Bolaamphiphile
  作者：Yu-Jing Tian、En-Tai Shi、Yu-Kui Tian、Ri-Sheng Yao、Feng Wang

  DOI：10.1021/ol500752b

  日期：2014.6.20

  A platinum(II) acetylide-based bolaamphiphile equipped with two peripheral B18C6 moieties has been successfully prepared, which demonstrates cooperative recognition behavior toward l-alanine ester salt in chloroform. In a polar methanol/chloroform (3/1, v/v) medium, the amino acid additives influence the aggregation of the bolaamphiphile significantly, leading to the morphological transition from nanospherical to disordered structures. The adaptive properties of the current host-guest binary system will benefit the development of stimuli-responsive supramolecular materials.