dimethyl 5-(3-hydroxypropoxy)isophthalate | 197232-37-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: dimethyl 5-(3-hydroxypropoxy)isophthalate
• 英文别名: Dimethyl 5-(3-hydroxypropoxy)benzene-1,3-dicarboxylate；dimethyl 5-(3-hydroxypropoxy)benzene-1,3-dicarboxylate
• CAS: 197232-37-4
• 化学式: C₁₃H₁₆O₆
• 分子量: 268.266
• InChiKey: DGFQMCFMRHEVHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  82.1
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  dimethyl 5-(3-hydroxypropoxy)isophthalate 、 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl-[(1->4)-(2,3,6-tri-O-acetyl-α-D-glucopyranosyl)](4)-(1->4)-2,3,6-tri-O-acetyl-D-glucopyranosyl trichloroacetatimidate 在 吡啶 、 三氟化硼乙醚 作用下， 以 二氯甲烷 为溶剂， 以39.5%的产率得到dimethyl 5-(3-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl-[(1->4)-2,3,6-tri-O-acetyl-α-D-glucopyranosyl](4)-(1->4)-2,3,6-tri-O-acetyl-β-D-glucopyranosyloxy)propoxy)isophthalate
  参考文献：
  名称：

  Glycodynamers: Dynamic Polymers Bearing Oligosaccharides Residues − Generation, Structure, Physicochemical, Component Exchange, and Lectin Binding Properties

  摘要：

  Dynamic glycopolymers have been generated by polycondensation through acylhydrazone formation between components bearing lateral bioactive oligosaccharide chains. They have been characterized as bottlebrush type by cryo-TEM and SANS studies. They present remarkable fluorescence properties whose emission wavelengths depend on the constitution of the polymer and are tunable by constitutional modification through exchange/incorporation of components, thus also demonstrating their dynamic character. Constitution-dependent binding of these glycodynamers to a lectin, peanut agglutinin, has been demonstrated.

  DOI：

  10.1021/ja9082733
• 作为产物：
  描述：

  5-羟基间苯二甲酸二甲酯 、 1,3-丙二醇 在 偶氮二甲酸二异丙酯 、 三苯基膦 作用下， 以 四氢呋喃 为溶剂， 以67%的产率得到dimethyl 5-(3-hydroxypropoxy)isophthalate
  参考文献：
  名称：

  Glycodynamers: Dynamic Polymers Bearing Oligosaccharides Residues − Generation, Structure, Physicochemical, Component Exchange, and Lectin Binding Properties

  摘要：

  Dynamic glycopolymers have been generated by polycondensation through acylhydrazone formation between components bearing lateral bioactive oligosaccharide chains. They have been characterized as bottlebrush type by cryo-TEM and SANS studies. They present remarkable fluorescence properties whose emission wavelengths depend on the constitution of the polymer and are tunable by constitutional modification through exchange/incorporation of components, thus also demonstrating their dynamic character. Constitution-dependent binding of these glycodynamers to a lectin, peanut agglutinin, has been demonstrated.

  DOI：

  10.1021/ja9082733

文献信息

• Glycodynamers: Dynamic Polymers Bearing Oligosaccharides Residues − Generation, Structure, Physicochemical, Component Exchange, and Lectin Binding Properties
  作者：Yves Ruff、Eric Buhler、Sauveur-Jean Candau、Ellina Kesselman、Yeshayahu Talmon、Jean-Marie Lehn

  DOI：10.1021/ja9082733

  日期：2010.3.3

  Dynamic glycopolymers have been generated by polycondensation through acylhydrazone formation between components bearing lateral bioactive oligosaccharide chains. They have been characterized as bottlebrush type by cryo-TEM and SANS studies. They present remarkable fluorescence properties whose emission wavelengths depend on the constitution of the polymer and are tunable by constitutional modification through exchange/incorporation of components, thus also demonstrating their dynamic character. Constitution-dependent binding of these glycodynamers to a lectin, peanut agglutinin, has been demonstrated.