(2-(dimethylamino)-2-oxo-1-(triphenyl-l5-phosphaneyl)ethyl)gold(II) chloride | 138176-25-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2-(dimethylamino)-2-oxo-1-(triphenyl-l5-phosphaneyl)ethyl)gold(II) chloride
• CAS: 138176-25-7
• 化学式: C₂₂H₂₂AuClNOP
• 分子量: 579.816
• InChiKey: RIWYJJBKJZTAIE-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  3.63
• 重原子数：
  27.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  20.31
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  (2-(dimethylamino)-2-oxo-1-(triphenyl-l5-phosphaneyl)ethyl)gold(II) chloride 在 Cl₂ 作用下， 以 四氯化碳 、 二氯甲烷 为溶剂， 以83%的产率得到(2-(dimethylamino)-2-oxo-1-(triphenyl-l5-phosphaneyl)ethyl)gold(IV) chloride
  参考文献：
  名称：

  Synthesis and structural characterization of gold-(I), -(III) and silver(I) complexes of the ylide ligand Ph₃PCHC(O)NMe₂. Crystal structure of [(AuPPh₃)₂{µ-C(PPh₃)C(O)NMe₂}]ClO₄

  摘要：

  The reaction between [AuCl(tht)] (tht = tetrahydrothiophene) and the ylide Ph3P = CHC(O)NMe2 gives [AuCl{CH(PPh3)C(O)NMe2}] 1, which reacts with chlorine to give [AuCl3{CH(PPh3)C(O)-NMe2}] 2 and with the same ylide and NaClO4 to form [Au{CH(PPh3)C(O)NMe2}2]ClO4 3. The analogous silver complex [Ag{CH(PPh3)C(O)NMe2}2]ClO4 4 is obtained by the reaction of AgClO4 with the ylide in molar ratio 1:2. The phosphonium salt [Ph3PCH2C(O)NMe2]ClO4 reacts with [Au(acac)(PPh3)] (acac = acetylacetonate) to give [Au{CH(PPh3)C(O)NMe2}(PPh3)]ClO4 5 or [(AuPPh3)2{mu-C(PPh3)C(O)NMe2}]ClO4 6 depending on the reaction conditions. The structure of 6 was confirmed by an X-ray diffraction study at -95-degrees-C [space group P1BAR, a = 11.572(3), b = 11.836(3), c = 21.627(7) angstrom, alpha = 78.29(2), beta = 87.19(2), gamma = 75.65(2)-degrees, R = 0.076]; the Au...Au bond length is 2.938(1) angstrom.

  DOI：

  10.1039/dt9910002579
• 作为产物：
  描述：

  (tetrahydrothiophene)gold(I) chloride 、 dimethylcarbamoylmethylenetriphenylphosphorane 以 二氯甲烷 为溶剂， 以63%的产率得到(2-(dimethylamino)-2-oxo-1-(triphenyl-l5-phosphaneyl)ethyl)gold(II) chloride
  参考文献：
  名称：

  Synthesis and structural characterization of gold-(I), -(III) and silver(I) complexes of the ylide ligand Ph₃PCHC(O)NMe₂. Crystal structure of [(AuPPh₃)₂{µ-C(PPh₃)C(O)NMe₂}]ClO₄

  摘要：

  The reaction between [AuCl(tht)] (tht = tetrahydrothiophene) and the ylide Ph3P = CHC(O)NMe2 gives [AuCl{CH(PPh3)C(O)NMe2}] 1, which reacts with chlorine to give [AuCl3{CH(PPh3)C(O)-NMe2}] 2 and with the same ylide and NaClO4 to form [Au{CH(PPh3)C(O)NMe2}2]ClO4 3. The analogous silver complex [Ag{CH(PPh3)C(O)NMe2}2]ClO4 4 is obtained by the reaction of AgClO4 with the ylide in molar ratio 1:2. The phosphonium salt [Ph3PCH2C(O)NMe2]ClO4 reacts with [Au(acac)(PPh3)] (acac = acetylacetonate) to give [Au{CH(PPh3)C(O)NMe2}(PPh3)]ClO4 5 or [(AuPPh3)2{mu-C(PPh3)C(O)NMe2}]ClO4 6 depending on the reaction conditions. The structure of 6 was confirmed by an X-ray diffraction study at -95-degrees-C [space group P1BAR, a = 11.572(3), b = 11.836(3), c = 21.627(7) angstrom, alpha = 78.29(2), beta = 87.19(2), gamma = 75.65(2)-degrees, R = 0.076]; the Au...Au bond length is 2.938(1) angstrom.

  DOI：

  10.1039/dt9910002579

文献信息

• Synthesis and Reactivity of Metal Complexes with Acyclic (Amino)(Ylide)Carbene Ligands
  作者：Elisa González-Fernández、Jörg Rust、Manuel Alcarazo

  DOI：10.1002/anie.201305311

  日期：2013.10.18

  No cycle required: The straightforward synthesis of acyclic (amino)(ylide)carbene gold complexes was achieved by reaction of isocyanide gold complexes with phosphorus and arsenic ylides as well as electron‐rich olefins. Their ability to form bimetallic species and to act as ligand‐transfer reagents has also been established.

  无需循环：通过异氰酸酯金络合物与磷，砷化氢以及富电子烯烃的反应，可以直接合成无环（氨基）（内酯）卡宾金络合物。它们形成双金属物质并充当配体转移试剂的能力也已确立。