1-benzyl-3-tert-butyl-1H-isotellurochromene | 211509-06-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-benzyl-3-tert-butyl-1H-isotellurochromene
• CAS: 211509-06-7
• 化学式: C₂₀H₂₂Te
• 分子量: 389.995
• InChiKey: OVYRKVUWPZRSIJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.08
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-benzyl-3-tert-butyl-1H-isotellurochromene 在 间氯过氧苯甲酸 作用下， 以 氯仿 为溶剂， 以58%的产率得到(Z)-1-benzylidene-3-tert-butylisotellurochromene
  参考文献：
  名称：

  Studies on chalcogen-containing heterocycles. Part 37: m-CPBA oxidation of isotellurochromenes and isoselenochromenes

  摘要：

  The oxidation of the 1-unsubstituted isotellurochromenes and isoselenochromenes with m-CPBA resulted in a novel ring-opening reaction to give the o-formyl distyryl ditellurides and diselenides as the sole products in good yields, respectively. The o-benzoyl distyryl ditelluride and diselenide were also produced from the corresponding 1-phenylisochromenes. In contrast, the 1-benzyl and 1-n-butylisochromenes were oxidized to afford the (Z)-1-benzylideneisochromenes and (Z)-1-butylideneisochromenes under similar conditions; no distyryl compounds were obtained. The distyryl compounds were also obtained by the hydrolysis of the corresponding 2-benzochalcogenopyrylium salts, which were easily converted from the 2-benzoisochromenes by treatment with triphenylcarbenium tetrafluoroborate (Ph3C+BF4-). (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.07.023
• 作为产物：
  描述：

  3-tert-butyl-1H-isotellurochromene 在 trityl tetrafluoroborate 作用下， 以 乙醚 、 硝基甲烷 为溶剂， 反应 1.0h， 生成 1-benzyl-3-tert-butyl-1H-isotellurochromene
  参考文献：
  名称：

  Studies on tellurium-containing heterocycles. Part 10.1 2-Benzotelluropyrylium salts: first preparation and reactions with Grignard reagents

  摘要：

  本文介绍了首次通过两个步骤从邻乙炔基苄基溴化物 1 简单制备 2-苯并四氢吡喃盐 4 的方法，以及这些盐 4 与苄基溴化镁和其他格氏试剂的特征反应。

  DOI：

  10.1039/a804036b

文献信息

• Studies on Tellurium-Containing Heterocycles. Part 20. Reactions of 2-Benzoselenopyrylium Salts and 2-Benzotelluropyrylium Salts with Nucleophiles: Formation of 1-Functionalized 1H-Isoselenochromenes and 1H-Isotellurochromenes
  作者：Haruki Sashida、Kazuo Ohyanagi

  DOI：10.1248/cpb.52.57

  日期：——

  were produced by the reaction of the salts 1 with Grignard reagents, were converted to the corresponding 1,3-disubstituted 2-benzopyrylium salts (14-17, 19) by treatment with triphenylcarbenium tetrafluoroborate (Ph(3)C(+) BF(4)(-)), respectively. The 1-benzylselenopyrylium salts (19A) and 1-benzyltelluropyrylium salts (19B) exist in the solvent as an equilibrium mixture of the salts (19) and the corresponding

  研究了2-苯并硒基吡啶鎓（1A）和2-苯并碲基吡啶鎓阳离子（1B）与各种亲核试剂的反应。LiAlH（4），醇钠（NaOMe，NaOi-Pr和NaOt-Bu），二乙胺，正丁胺和丙酮与1反应生成1H-异色酮（2）和相应的1取代的产物（4-9）在温和条件下几乎可以达到高产。通过盐1与格利雅试剂反应生成的1-烷基（苯基）异硒烯二酮（10-13）和1-苄基异铬烯酮（18A，18B）被转化为相应的1,3-二取代的2-苯并吡啶鎓分别用四氟硼酸三苯基碳鎓（Ph（3）C（+）BF（4）（-））处理盐（14-17，19）。
• Studies on chalcogen-containing heterocycles. Part 37: m-CPBA oxidation of isotellurochromenes and isoselenochromenes
  作者：Haruki Sashida、Mamoru Kaname、Kazuo Ohyanagi、Mao Minoura

  DOI：10.1016/j.tet.2012.07.023

  日期：2012.12

  The oxidation of the 1-unsubstituted isotellurochromenes and isoselenochromenes with m-CPBA resulted in a novel ring-opening reaction to give the o-formyl distyryl ditellurides and diselenides as the sole products in good yields, respectively. The o-benzoyl distyryl ditelluride and diselenide were also produced from the corresponding 1-phenylisochromenes. In contrast, the 1-benzyl and 1-n-butylisochromenes were oxidized to afford the (Z)-1-benzylideneisochromenes and (Z)-1-butylideneisochromenes under similar conditions; no distyryl compounds were obtained. The distyryl compounds were also obtained by the hydrolysis of the corresponding 2-benzochalcogenopyrylium salts, which were easily converted from the 2-benzoisochromenes by treatment with triphenylcarbenium tetrafluoroborate (Ph3C+BF4-). (C) 2012 Elsevier Ltd. All rights reserved.
• Studies on tellurium-containing heterocycles. Part 10.1 2-Benzotelluropyrylium salts: first preparation and reactions with Grignard reagents
  作者：Haruki Sashida、Kazuo Ohyanagi

  DOI：10.1039/a804036b

  日期：——

  The first simple preparation of 2-benzotelluropyrylium salts 4 from o-ethynylbenzyl bromides 1 in two steps, and the characteristic reaction of these salts 4 with benzylmagnesium bromide and other Grignard reagents are described.

  本文介绍了首次通过两个步骤从邻乙炔基苄基溴化物 1 简单制备 2-苯并四氢吡喃盐 4 的方法，以及这些盐 4 与苄基溴化镁和其他格氏试剂的特征反应。