5α-ergostatriene-(7,14,22t)-triol-(3β,5,6α) | 71097-06-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 5α-ergostatriene-(7,14,22t)-triol-(3β,5,6α)
• 英文别名: 5α-ergostatriene-(7,14,22t)-triol-(3β,5,6α)；(10R)-3c,5t,6t-Trihydroxy-10r,13c-dimethyl-17c-((1R:4R)-1,4,5-trimethyl-hexen-(2t)-yl)-(9tH)-Δ^7,14-dodecahydro-1H-cyclopenta[a]phenanthren；3β,5,6α-Trihydroxy-10,13-dimethyl-17β-((1R:4R)-1,4,5-trimethyl-hexen-(2t)-yl)-5α-gonadien-(7,14)；24β_F-Methyl-5α-cholestatrien-(7,14,22t)-triol-(3β,5,6α)；(24R)-24-Methyl-5α-cholestatrien-(7,14,22t)-triol-(3β,5,6α)；5α-Ergostatrien-(7,14,22t)-triol-(3β,5,6α)；3β,5α,6α-Trihydroxyergosta-7,14,22-trien
• CAS: 71097-06-8
• 化学式: C₂₈H₄₄O₃
• 分子量: 428.656
• InChiKey: CEGIAAPCROLUDL-XJUJAIRASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.42
• 重原子数：
  31.0
• 可旋转键数：
  4.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  60.69
• 氢给体数：
  3.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  5α-ergostatriene-(7,14,22t)-triol-(3β,5,6α) 在 platinum(IV) oxide 氢气 、 溶剂黄146 作用下， 生成 5α-ergostene-(8(14))-triol-(3β,5,6α)
  参考文献：
  名称：

  Permanganate oxidation of ergosterol

  摘要：

  DOI：

  10.1021/jo01335a008
• 作为产物：
  描述：

  麦角固醇 在 potassium permanganate 作用下， 生成 5α-ergostatriene-(7,14,22t)-triol-(3β,5,6α)
  参考文献：
  名称：

  Permanganate oxidation of ergosterol

  摘要：

  DOI：

  10.1021/jo01335a008

文献信息

• Permanganate Oxidation of Ergosterol
  作者：Mary Fieser、Adolfo Quilico、Alex Nickon、William E. Rosen、E. James Tarlton、Louis F. Fieser

  DOI：10.1021/ja01112a057

  日期：1953.8
• Thrust-Washer Evaluation of Self-Lubricating PS304 Composite Coatings in High Temperature Sliding Contact
  作者：Thierry A. Blanchet、Jong-Hwan Kim、Salvadore J. Calabrese、Christopher Dellacorte

  DOI：10.1080/10402000208982579

  日期：2002.1

  PS304 self-lubricating composite coatings were successfully deposited on steel substrates at various plasma spray facilities using mixtures blended from commercially obtained constituent particles. Coatings were evaluated in thrust-washer tests against Inconel X-750 at low contact pressures to 40kPa, sliding speed of 5.4m/s, and either ambient temperature or 500 degreesC chosen to simulate conditions in air foil bearings during startup and shutdown contact. Wear factors for all PS304 coatings tested, regardless of contact pressure and temperature, ranged from 1-3*10(-4) mm(3)/Nm while coefficients of friction of approximately mu = 0.5 were measured in all cases. While wear and friction behavior of PS304 in air foil bearings appear to have been simulated, surface roughening was observed in these thrust-washer tests which used continuous sliding contact, as opposed to the evolution of smoother surfaces observed in high-temperature foil bearings experiencing cyclic startup/shutdown. Wear-induced surface smoothening of PS304 was additionally simulated in thrust-washer tests with sliding contact instead imposed intermittently.