methyl 4-acetoxymethyl-3-nitrobenzoate | 142386-70-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: methyl 4-acetoxymethyl-3-nitrobenzoate
• 英文别名: methyl 4-(acetyloxymethyl)-3-nitrobenzoate
• CAS: 142386-70-7
• 化学式: C₁₁H₁₁NO₆
• 分子量: 253.211
• InChiKey: GIYOQCJMFZBLNE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  98.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  methyl 4-acetoxymethyl-3-nitrobenzoate 在 氨 作用下， 以 甲醇 为溶剂， 以76%的产率得到4-(羟基甲基)-3-硝基苯甲酸甲酯
  参考文献：
  名称：

  Disaccharide synthesis on a soluble hyperbranched polymer

  摘要：

  A hyperbranched star polymer was employed as a soluble support for disaccharide synthesis as a practical alternative to a dendrimer support. The large number of terminal groups present on the support permit very high loading levels to be possible. Polymer bound intermediates could be directly analyzed by MALDI-TOF mass spectrometry due to the presence of a photolabile linker that is cleaved by the MALDI-TOF laser. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01709-8
• 作为产物：
  描述：

  4-溴甲基苯甲酸甲酯 在 硫酸 、 硝酸 、 sodium acetate 作用下， 生成 methyl 4-acetoxymethyl-3-nitrobenzoate
  参考文献：
  名称：

  Disaccharide synthesis on a soluble hyperbranched polymer

  摘要：

  A hyperbranched star polymer was employed as a soluble support for disaccharide synthesis as a practical alternative to a dendrimer support. The large number of terminal groups present on the support permit very high loading levels to be possible. Polymer bound intermediates could be directly analyzed by MALDI-TOF mass spectrometry due to the presence of a photolabile linker that is cleaved by the MALDI-TOF laser. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01709-8

文献信息

• Polymers having (1 → 4)- and (1 → 6)-linked α-d-glucopyranosyl groups as acceptors in the glycogen synthase reaction
  作者：Uri Zehavi、Mina Herchman、Sabine Köpper

  DOI：10.1016/s0008-6215(00)90563-9

  日期：1992.4

  Insoluble, light-sensitive polymers linked to maltose, maltotriose, a glycogen-branch point trisaccharide, and panose were synthesized and served in a comparative study as acceptors in the glycogen synthase (UDP-D-glucose:glycogen 4-alpha-D-glucosyltransferase, EC 2.4.1.11) reaction. The highest transfer rate was observed with the maltotrio polymer. Extending the acceptor linearly with (1 --> 4)-linked alpha-D-glucopyranosyl residues improved the transfer, whereas (1 --> 6)-linked alpha-D-glucopyranosyl branches decreased it.