2-(2,4-dimethyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-N-(2-morpholin-4-yl-ethyl)-acetamide | 14356-72-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2-(2,4-dimethyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-N-(2-morpholin-4-yl-ethyl)-acetamide
• 英文别名: 2-(2,4-dimethyl-6-oxo-1H-pyrimidin-5-yl)-N-(2-morpholin-4-ylethyl)acetamide
• CAS: 14356-72-0
• 化学式: C₁₄H₂₂N₄O₃
• 分子量: 294.354
• InChiKey: HTZYITUSNNCKLJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.5
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  83
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• COMPOSITIONS AND METHODS FOR DISRUPTING A MACROPHAGE NETWORK
  申请人：Scripps Health

  公开号：US20210187111A1

  公开（公告）日：2021-06-24

  Described herein are methods and compositions for disrupting a macrophage network. Described herein are targeting agents capable of targeting one or more cells of a macrophage network. Methods for treating various diseases, such as cancer and granulomatous diseases are provided.
• [EN] COMPOSITIONS AND METHODS FOR DISRUPTING A MACROPHAGE NETWORK<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR PERTURBER UN RÉSEAU DE MACROPHAGES
  申请人：SCRIPPS HEALTH

  公开号：WO2020018434A1

  公开（公告）日：2020-01-23

  Described herein are methods and compositions for disrupting a macrophage network. Described herein are targeting agents capable of targeting one or more cells of a macrophage network. Methods for treating various diseases, such as cancer and granulomatous diseases are provided.