4-氨基-2-羟基苯磺酸 | 5336-26-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-氨基-2-羟基苯磺酸
• 英文名称: 4-Amino-2-hydroxybenzenesulfonic acid
• 英文别名: 4-amino-2-hydroxy-benzenesulfonic acid；4-Amino-2-hydroxy-benzolsulfonsaeure；5-Amino-phenyl-sulfonsaeure-(2)；5-Amino-phenol-sulfonsaeure-(2)；2-hydroxy-4-aminobenzenesulfonic acid
• CAS: 5336-26-5
• 化学式: C₆H₇NO₄S
• mdl: MFCD11499088
• 分子量: 189.192
• InChiKey: GPLYAUJTVOYYTL-UHFFFAOYSA-N

物化性质

• 熔点：
  275 °C (decomp)
• 密度：
  1.675±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  109
• 氢给体数：
  3
• 氢受体数：
  5

安全信息

• 海关编码：
  2922299090

反应信息

• 作为反应物：
  描述：

  4-氨基-2-羟基苯磺酸 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Andre, Dissertation , S. 23, 27

  摘要：

  DOI：
• 作为产物：
  描述：

  2-氨基-4-羟基苯磺酸 在 硫酸 作用下， 生成 4-氨基-2-羟基苯磺酸
  参考文献：
  名称：

  DE70788

  摘要：

  公开号：

文献信息

• Colorant compounds
  申请人：Banning H. Jeffrey

  公开号：US20060020141A1

  公开（公告）日：2006-01-26

  Compounds of the formula wherein M is either (1) a metal ion having a positive charge of +y wherein y is an integer which is at least 2, said metal ion being capable of forming a compound with at least two chromogen moieties, or (2) a metal-containing moiety capable of forming a compound with at least two chromogen moieties, z is an integer representing the number of chromogen moieties associated with the metal and is at least 2, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , a, b, c, d, Y, and z are as defined herein, Q − is a COO − group or a SO 3 — group, A is an organic anion, and CA is either a hydrogen atom or a cation associated with all but one of the Q − groups.

  式中的化合物，其中M是一个带有正电荷+y的金属离子，其中y是至少为2的整数，该金属离子能够与至少两个色团基团形成化合物，或者M是一个含金属基团的基团，能够与至少两个色团基团形成化合物，z是表示与金属相关的色团基团数量的整数，至少为2，R1、R2、R3、R4、R5、R6、R7、a、b、c、d、Y和z的定义如上所述，Q-是一个COO-基团或SO3-基团，A是一个有机阴离子，CA是一个氢原子或与除一个Q-基团之外的所有Q-基团相关联的阳离子。
• Environmental protection series of reactive dyestuffs and their use
  申请人：Chen Hsiao-San

  公开号：US20050203286A1

  公开（公告）日：2005-09-15

  An environmental protection reactive dyestuff of the following formula (I) is disclosed, wherein R 1 , R 2 , D, M are defined as in the specification. The dyestuff of the invention is distinguished by a high fixation and a very good build-up. It is distinguished also by a green environmental protection and a low salt, a low base, a high exhaustion, non-contain heavy metal and halogen atoms, and it has fiber-reactive properties and is very highly suitable for dyeing and printing of materials containing either cellulose fibers, such as cotton, synthetic cotton, hemp, and synthetic hemp, or amide containing fibers such as wool and nylon.

  揭示了以下化学式(I)的一种环保反应性染料，其中R1、R2、D、M的定义如规范中所述。该发明的染料具有高固定性和非常良好的建立性。它还具有绿色环保、低盐、低碱、高耗尽、不含重金属和卤原子的特点，具有纤维反应性能，非常适合于含有纤维素纤维（如棉花、合成棉、大麻和合成大麻）或含酰胺纤维（如羊毛和尼龙）的材料的染色和印花。
• [EN] TETRAFLUOROBENZYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ACUTE AND CHRONIC NEURODEGENERATIVE DISEASES IN CENTRAL NERVOUS SYSTEM CONTAINING THE SAME<br/>[FR] DERIVES DE TETRAFLUOROBENZYLE ET COMPOSITION PHARMACEUTIQUE POUR LA PREVENTION ET LE TRAITEMENT DE MALADIES NEURODEGENERATIVES AIGUES ET CHRONIQUES AFFECTANT LE SYSTEME NERVEUX CENTRAL CONTENANT LESDITS DERIVES
  申请人：NEUROTECH CO LTD

  公开号：WO2004000786A1

  公开（公告）日：2003-12-31

  The present invention relates to a tetrafluorobenzyl derivative and a pharmaceutical composition for prevention and treatment of acute and chronic neurodegenerative diseases in central nervous system and ophthalmic diseases containing the same. The tetrafluorobenzyl derivative of the present invention can effectively be used to prevent and treat chronic neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Huntington's disease, degenerative brain disease such as epilepsy and ischemic brain disease such as stroke.

  本发明涉及一种四氟苯基衍生物和一种药物组合物，用于预防和治疗中枢神经系统和眼科疾病的急性和慢性神经退行性疾病。本发明的四氟苯基衍生物可以有效地用于预防和治疗慢性神经退行性疾病，如阿尔茨海默病、帕金森病和亨廷顿病，以及癫痫等退化性脑病和缺血性脑病，如中风。
• Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same
  申请人：Gwag Byoung-Joo

  公开号：US20050239896A1

  公开（公告）日：2005-10-27

  The present invention relates to a tetrafluorobenzyl derivative and a pharmaceutical composition for prevention and treatment of acute and chronic neurodegenerative disease in central nervous system and ophthalmic diseases containing the same. The tetrafluorobenzyl derivative of the present invention can effectively be used to prevent and treat chronic neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Huntington's disease, degenerative brain disease such as epilepsy and ischemic brain disease such as stroke.

  本发明涉及一种四氟苯甲基衍生物及其制备方法，以及一种用于预防和治疗中枢神经系统和眼科疾病的药物组合物，其中包含该四氟苯甲基衍生物。本发明的四氟苯甲基衍生物可有效用于预防和治疗慢性神经退行性疾病，如阿尔茨海默病、帕金森病和亨廷顿病，退行性脑病，如癫痫和缺血性脑病，如中风。
• PHASE CHANGE INKS CONTAINING COLORANT COMPOUNDS
  申请人：Wu Bo

  公开号：US20050016417A1

  公开（公告）日：2005-01-27

  Phase change inks comprising a carrier and a colorant of the formula wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , a, b, c, d, Y, Q Q − , A, and CA are as defined herein.

  相变油墨包括载体和颜料，其化学式为：其中R1，R2，R3，R4，R5，R6，R7，a，b，c，d，Y，Q Q−，A和CA的定义如本文所述。