4-氨基-3-氯-吡啶-2-羧酸 | 76165-18-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 4-氨基-3-氯-吡啶-2-羧酸
• 英文名称: 4-Amino-3-chloropyridine-2-carboxylic acid
• CAS: 76165-18-9
• 化学式: C₆H₅ClN₂O₂
• mdl: MFCD04114095
• 分子量: 172.571
• InChiKey: NLMORBPDRBXCCD-UHFFFAOYSA-N

物化性质

• 沸点：
  406.8±45.0 °C(Predicted)
• 密度：
  1.577±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  76.2
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  4-氨基-3,5,6-三氯吡啶羧酸 在 铁粉 作用下， 以 phosphate buffer 为溶剂， 反应 0.33h， 生成 2-(羟甲基)-4-氨基吡啶 、 4-氨基吡啶-2-甲酸 、 4-氨基-3-氯-吡啶-2-羧酸 、 4-氨基-6-氯吡啶-2-羧酸
  参考文献：
  名称：

  Degradation of benomyl, picloram, and dicamba in a conical apparatus by zero-valent iron powder

  摘要：

  Reduction of some pesticides (benomyl, picloram, and dicamba) was studied in an aerobic batch conical pilot system to investigate the disappearance of these pesticides on contact with iron powder (20 g/l, 325-mesh). Aqueous buffered solutions of the compounds were added to the system followed by zero-valent iron powder (ZVIP), and the decline in the pesticide concentrations was monitored over time. HPLC analyses show a complete disappearance of picloram (1.20 mg/l) after 20 min of reaction. Benomyl (1.00 mg/l) and dicamba (1.25 mg/l) disappear after 25 and 40 min, respectively. The t(50) values ranged From 3 to 5.5 min, and were about slightly less than the t(1/2) values reported when the log of the relative HPLC peak area was plotted versus time, where the relative peak area was calculated by dividing the measured peak area by the initial peak area. Pathways for the degradation of the studied pesticides by ZVIP are proposed. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0045-6535(00)00184-3

文献信息

• 4-aminopicolinates and their use as herbicides
  申请人：——

  公开号：US20010047099A1

  公开（公告）日：2001-11-29

  4-Aminopicolinic acids, having halogen, alkoxy, alkylthio, aryloxy, heteroaryloxy or trifluoromethyl substituents in the 3-, 5- and 6-positions, and their amine and acid derivatives are potent herbicides demonstrating a broad spectrum of weed control.

  具有卤素，烷氧基，烷硫基，芳氧基，杂环芳氧基或三氟甲基取代基的4-氨基吡啶酸衍生物，在3-，5-和6-位置上，以及它们的胺和酸衍生物是强效除草剂，具有广谱的杂草控制作用。
• 4-Aminopicolinates and their use as herbicides
  申请人：Dow AgroSciences LLC

  公开号：EP1498413A1

  公开（公告）日：2005-01-19

  4-Aminopicolinic acids, having halogen, alkoxy, alkylthio, aryloxy, heteroaryloxy or trifluormethyl substituents in the 3-, 5- and 6-positions, and their amine and acid derivatives of formula (I) wherein X represents H, halogen, C1-C6 alkoxy, C1-C6 alkylthio, aryloxy, nitro, or trifluoromethyl; Y represents halogen, C1-C6 alkoxy, C1-C6 alkylthio, aryloxy, heteroaryloxy or trifluoromethyl; Z represents halogen, C1-C6 alkoxy, C1-C6 alkylthio, aryloxy or nitro; and W represents -NO2, -N3, -NR1R2, -N=CR3R4 or -NHN=CR3R4 are potent herbiciedes demonstrating a broad spectrum of weed control.

  在 3-、5-和 6-位上具有卤素、烷氧基、烷硫基、芳氧基、杂芳氧基或三氟甲基取代基的 4-氨基吡啶甲酸及其式 (I) 的胺和酸衍生物 其中 X 代表 H、卤素、C1-C6 烷氧基、C1-C6 烷硫基、芳氧基、硝基或三氟甲基；Y 代表卤素、C1-C6 烷氧基、C1-C6 烷硫基、芳氧基、杂芳氧基或三氟甲基；Z 代表卤素、C1-C6 烷氧基、C1-C6 烷硫基、芳氧基、杂芳氧基或三氟甲基；Y代表卤素、C1-C6烷氧基、C1-C6烷硫基、芳氧基、杂芳氧基或三氟甲基；Z代表卤素、C1-C6烷氧基、C1-C6烷硫基、芳氧基或硝基；W代表-NO2、-N3、-NR1R2、-N=CR3R4或-NHN=CR3R4。
• 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES
  申请人：Dow Agrosciences LLC

  公开号：EP1246802A1

  公开（公告）日：2002-10-09
• US6297197B1
  申请人：——

  公开号：US6297197B1

  公开（公告）日：2001-10-02
• [EN] 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES<br/>[FR] 4-AMINOPICOLINATES ET LEURS UTILISATIONS COMME HERBICIDES
  申请人：DOW AGROSCIENCES LLC

  公开号：WO2001051468A1

  公开（公告）日：2001-07-19

  4-Aminopicolinic acids, having halogen, alkoxy, alkylthio, aryloxy, heteroaryloxy or trifluoromethyl substituents in the 3-, 5- and 6-positions, and their amine and acid derivatives of formula (I) wherein X represents H, halogen, C1-C6 alkoxy, C1-C6 alkylthio, aryloxy, nitro, or trifluoromethyl; Y represents halogen, C1-C6 alkoxy, C1-C6 alkylthio, aryloxy, heteroaryloxy or trifluoromethyl; Z represents halogen, C1-C6 alkoxy, C1-C6 alkylthio, aryloxy or nitro; and W represents -NO2, -N3, -NR1R2, -N=CR3R4 or -NHN=CR3R4 are potent herbicides demonstrating a broad spectrum of weed control.