(4S,5S)-4-benzyl-5-(2-benzyprop-2-enyl)-1,3-oxazolidin-2-one | 565454-79-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: (4S,5S)-4-benzyl-5-(2-benzyprop-2-enyl)-1,3-oxazolidin-2-one
• CAS: 565454-79-7
• 化学式: C₂₀H₂₁NO₂
• 分子量: 307.392
• InChiKey: RNWLGVKHMGZGGS-OALUTQOASA-N

反应信息

• 作为产物：
  描述：

  三光气 、 (2S,3S)-2-amino-5-benzyl-1-phenylhex-5-en-3-ol 以 二氯甲烷 为溶剂， 反应 3.0h， 以46 mg的产率得到(4S,5S)-4-benzyl-5-(2-benzyprop-2-enyl)-1,3-oxazolidin-2-one
  参考文献：
  名称：

  An efficient procedure for the synthesis of 2-N-Boc-amino-3,5-diols

  摘要：

  AWe wish to describe here the diastereoselective reaction between chiral N-Boc-alpha-amino aldehydes with both achiral allyltrichlorostannanes leading to 1,2-syn-N-Boc-alpha-amino alcohols, which are easily converted to the corresponding 4-N-Boc-amino-3-hydroxy ketones after treatment with catalytic amounts of OsO4 in the presence of NaIO4. After reduction of the carbonyl function, these 4-N-Boc-amino-3-hydroxy ketones were converted to 1-deoxy-5-hydroxy sphingosine analogues. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.04.049