4-氨基-N-(4-氨基-2-甲基苯基)苯甲酰胺 | 14303-59-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-氨基-N-(4-氨基-2-甲基苯基)苯甲酰胺
• 英文名称: 4-amino-N-(4-amino-2-methylphenyl)benzamide
• 英文别名: 4-amino-benzoic acid-(4-amino-2-methyl-anilide)；2-Methyl-N¹-(4-amino-benzoyl)-p-phenylendiamin；4-Amino-benzoesaeure-(4-amino-2-methyl-anilid)；4,4'-diamino-2'methyl-benzanilide
• CAS: 14303-59-4
• 化学式: C₁₄H₁₅N₃O
• mdl: MFCD00600434
• 分子量: 241.293
• InChiKey: YCSQADLXNHJXCN-UHFFFAOYSA-N

物化性质

• 沸点：
  388.7±42.0 °C(Predicted)
• 密度：
  1.275±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  81.1
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-硝基-2-甲苯胺 生成 4-氨基-N-(4-氨基-2-甲基苯基)苯甲酰胺
  参考文献：
  名称：

  Diazo compounds obtained by coupling acetoacetanilides with tetrazotized

  摘要：

  具有绿色色调的黄色颜料由以下公式表示：##STR1## 其中X.sub.1和X.sub.2可以相同或不同，每个都是氢、卤素（氯、氟或溴）、低烷基或具有1至3个碳原子的烷氧基；R.sub.1和R.sub.2可以相同或不同，每个都是来自酰基-乙酰-氨基-芳香偶联剂或吡唑酮偶联剂的残基。通过将（1）乙酰-乙酰-氨基-芳香化合物或（2）吡唑酮与4,4'-二氨基苯基甲酰胺偶联来获得颜料。这些黄色颜料具有高染色产率、高色调纯度（亮度）、良好的耐光性和良好的有机溶剂抵抗性的特点。这些颜料在彩色印刷行业中特别有用。

  公开号：

  US04269769A1

文献信息

• POLYIMIDE PRECURSOR, POLYIMIDE, AND MATERIALS TO BE USED IN PRODUCING SAME
  申请人：Takasawa Ryoichi

  公开号：US20130178597A1

  公开（公告）日：2013-07-11

  Disclosed is a novel co-polyimide precursor for producing a polyimide having high transparency. The co-polyimide precursor comprises a unit structure represented by general Formula (A1) and a unit structure represented by general Formula (A2): wherein, in general Formula (A1), R 1 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; and R 2 and R 3 each independently represent a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or an alkylsilyl group having 3 to 9 carbon atoms, wherein, in general Formula (A2), R 4 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; R 5 and R 6 each independently represent a hydrogen, an alkyl group having 1 to 6 carbon atoms, or an alkylsilyl group having 3 to 9 carbon atoms; and X represents a tetravalent group other than those represented by Formulae (A3):

  本发明涉及一种新型共聚酰亚胺前体，用于制备具有高透明度的聚酰亚胺。该共聚酰亚胺前体包括由通式（A1）表示的单元结构和由通式（A2）表示的单元结构：其中，在通式（A1）中，R1表示氢原子或具有1至4个碳原子的烷基基团；R2和R3各自独立地表示氢原子、具有1至6个碳原子的烷基基团或具有3至9个碳原子的烷基硅基团，在通式（A2）中，R4表示氢原子或具有1至4个碳原子的烷基基团；R5和R6各自独立地表示氢原子、具有1至6个碳原子的烷基基团或具有3至9个碳原子的烷基硅基团；X表示除通式（A3）所表示的四价基团以外的四价基团。
• THERMOPLASTIC POLYIMIDE, AND LAMINATED POLYIMIDE FILM AND METAL FOIL-LAMINATED POLYIMIDE FILM USING THE THERMOPLASTIC POLYIMIDE
  申请人：Toray Industries, Inc.

  公开号：EP2039715A1

  公开（公告）日：2009-03-25

  Disclosed is a thermoplastic polyimide which has excellent heat resistance and can adhere to a metal foil by thermocompression bonding for a short-time. The thermoplastic polyimide comprising a tetracarboxylic dianhydride residue and a diamine residue wherein the biphenyl tetracarboxylic dianhydride residues account for 80 mol% or more of the total tetracarboxylic dianhydride residues, the 4,4'-diaminodiphenyl ether residues for 65 mol% or more and 85 mol% or less of the total diamine residues, and the paraphenylene diamine residues for 15 mol% or more and 35 mol% or less of the total diamine residues.

  本发明公开了一种热塑性聚酰亚胺，该聚酰亚胺具有优异的耐热性，并能通过热压粘合短时间粘附在金属箔上。该热塑性聚酰亚胺由四羧酸二酐残基和二胺残基组成，其中联苯四羧酸二酐残基占四羧酸二酐残基总量的 80 摩尔%或以上、4,4'-二氨基二苯醚残留物占二元胺残留物总量的 65 mol% 或以上，85 mol% 或以下；对苯二胺残留物占二元胺残留物总量的 15 mol% 或以上，35 mol% 或以下。
• Photosensitive resin composition, and polymer film made therefrom
  申请人：Zhen Ding Technology Co., Ltd.

  公开号：US10928730B2

  公开（公告）日：2021-02-23

  A photosensitive resin composition comprises a modified polyimide polymer having a chemical structural formula of: photosensitive monomers, a bisphenol A epoxy resin, a photo-initiator, and a pigment. The modified polyimide polymer is made by a reaction of a polyimide polymer having a chemical structural formula of: and glycidyl methacrylate. The carboxyl group of the polyimide polymer reacts with the epoxy group of glycidyl methacrylate. The polyimide polymer is made by a reaction of dianhydride monomers each having an A group, diamine monomers each having the R group, diamine monomers each having the R1 group, and diamine monomers each having the R2 group. The diamine monomer having R group is a diamine compound having R group bonding with the carboxyl group. The diamine monomer having R1 group is a soft long-chain diamine monomer. R2 group comprises at least one secondary amine group or tertiary amine group.

  一种光敏树脂组合物包含一种改性聚酰亚胺聚合物，其化学结构式为 光敏单体、双酚 A 环氧树脂、光引发剂和颜料。改性聚酰亚胺聚合物是由具有以下化学结构式的聚酰亚胺聚合物反应制成的： 和甲基丙烯酸缩水甘油酯。聚酰亚胺聚合物的羧基与甲基丙烯酸缩水甘油酯的环氧基发生反应。聚酰亚胺聚合物是由具有 A 基团的二酐单体、具有 R 基团的二胺单体、具有 R1 基团的二胺单体和具有 R2 基团的二胺单体反应而成。具有 R 基的二胺单体是具有与羧基成键的 R 基的二胺化合物。具有 R1 基团的二胺单体是软长链二胺单体。R2 基团包括至少一个仲胺基团或叔胺基团。
• Anticonvulsant Profile of 4-Amino-(2-methyl-4-aminophenyl)benzamide in Mice and Rats
  作者：Martial R. Kanyonyo、Jacques H. Poupaert、Didier M. Lambert

  DOI：10.1111/j.1600-0773.1998.tb01397.x

  日期：1998.1

  Abstract: An original ameltolide analogue 4‐amino‐(2‐methyl‐4‐aminophcnyl)benzamide, in which a second amino group has been introduced, was synthesized and evaluated for anticonvulsant activity. After intraperitoneal administration to mice, 4‐amino‐(2‐methyl‐4‐aminophenyl)benzamide was found active in the maximal electroshock seizure test and against the tonic seizures elicited either by bicuculline or 3‐mercaptopropionic acid. 4‐amino‐(2‐methyl‐4‐arainophenyl)benzamidc (4A‐2M4A‐PB) gave anti maximal electroshock seizures ED50, of 63 umol/kg (15.4 mg/kg) and a TD50 of 676 μmol/kg (163 mg/kg), yielding a PI of 10.7: the potency is similar to that of the 4‐amino‐(2‐rnethyl‐3‐aminophenyl)phthalimide (4‐A‐2M3A‐PP), superior to that of 4‐amino‐(2,6‐dimethylphenyl)phlhaiimide (4A‐2,6‐DMPP), close to that of phenytoin and carbamazepine and inferior to that of ameltolide. 4A‐2M4A‐PB with an ED50 of 41 [28‐60] μmol/kg (9.9 mg/kg) is as active after oral administration to rats as carbamazepine, more active than ameltolide, 4‐A‐2M3A‐PP and phenytoin and slightly less active than the 4A‐2,6‐DMPP. The introduction of a second amino group on the substituted phenyl ring does not affect drastically the anticonvulsant potency after intraperitoneal administration to mice; moreover, it seems to enhance the activity after oral administration. 4A‐2M4A‐PB is a good candidate both for further pharmacokinetic studies and for the study of the precise mechanism of action.
• Substituted benzanilides and the process for their preparation
  申请人：DU PONT

  公开号：US02150190A1

  公开（公告）日：1939-03-14