4-(Phenylmethoxy)-2,5-morpholinedione 2-[O-(phenylmethyl)oxime] | 140405-37-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(Phenylmethoxy)-2,5-morpholinedione 2-[O-(phenylmethyl)oxime]
• 英文别名: 4-phenylmethoxy-6-phenylmethoxyiminomorpholin-3-one
• CAS: 140405-37-4
• 化学式: C₁₈H₁₈N₂O₄
• 分子量: 326.352
• InChiKey: JKTIGYFCISZIDI-UHFFFAOYSA-N

物化性质

• 沸点：
  463.7±55.0 °C(Predicted)
• 密度：
  1.21±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.51
• 重原子数：
  24.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  60.36
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  2-氯-N-苯基甲氧基乙酰胺 以 N,N-二甲基甲酰胺 为溶剂， 以48%的产率得到N-benzyloxyacetamide
  参考文献：
  名称：

  Electrochemical studies on haloamides. Part 3. Haloacetamides and halo-acetohydroxamates

  摘要：

  The electrochemical reduction of haloacetamides and acetohydroxamates 1 and 2 at a mercury cathode in DMF-0.1 mol dm-3 TEAP (tetraethylammonium perchlorate) solutions has been investigated.The reduction leads to the corresponding dehalogenated products together with cyclic dimers, arising from follow-up reactions of the conjugated base of the starting compound. The same type of products, but in quite different yield, are formed when ethyl isobutyrate anion is electrogenerated in the presence of chloro derivatives 1. The reactivity of the substrates, and in particular the structure of the dimers, primarily depends on the nature of the substituent at the amide nitrogen. Possible reaction pathways leading to the products are suggested.

  DOI：

  10.1039/p19920000375

文献信息

• Casadei, Maria Antonietta; Rienzo, Barbara Di; Inesi, Achille, Journal of the Chemical Society. Perkin transactions I, 1992, # 3, p. 379 - 382
  作者：Casadei, Maria Antonietta、Rienzo, Barbara Di、Inesi, Achille、Moracci, Franco Micheletti

  DOI：——

  日期：——