N-Isopropyl-N-propyl-ethylendiamin | 14165-23-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-Isopropyl-N-propyl-ethylendiamin
• 英文别名: (2-Aminoethyl)(propan-2-yl)propylamine；N'-propan-2-yl-N'-propylethane-1,2-diamine
• CAS: 14165-23-2
• 化学式: C₈H₂₀N₂
• 分子量: 144.26
• InChiKey: YCCRRIYVKYVTHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-Isopropyl-N-propyl-ethylendiamin 、 2-甲基-2-疏基硫酸脲 生成 <2-(Isopropyl-propyl-amino)-ethyl>-guanidin
  参考文献：
  名称：

  Pasini; Coda; Colò, Farmaco, Edizione Scientifica, 1965, vol. 20, # 10, p. 673 - 685

  摘要：

  DOI：
• 作为产物：
  描述：

  N-(2-溴乙基)邻苯二甲酰亚胺 、 N-异丙基丙胺 生成 N-Isopropyl-N-propyl-ethylendiamin
  参考文献：
  名称：

  Pasini; Coda; Colò, Farmaco, Edizione Scientifica, 1965, vol. 20, # 10, p. 673 - 685

  摘要：

  DOI：

文献信息

• 2-Methoxy-6-chloro-9-(N-substituted-amino)-acridines. II. Compounds Derived from Cyclic Secondary Amines¹
  作者：Joseph Corse、J. T. Bryant、H. A. Shonle

  DOI：10.1021/ja01214a012

  日期：1946.10
• ACETAMIDE THIENOTRIAZOLODIAZEPINES AND USES THEREOF
  申请人：Dana-Farber Cancer Institute, Inc.

  公开号：US20210093644A1

  公开（公告）日：2021-04-01

  The present invention provides compounds of Formula (I), and pharmaceutically compositions thereof. Compounds of Formula (I) are binders of bromodomains and/or bromodomain-containing proteins (e.g., bromo and extra terminal (BET) proteins). Also provided are methods, uses, and kits using the compounds and pharmaceutical compositions for inhibiting the activity (e.g., increased activity) of bromodomains and/or bromodomain-containing proteins and for treating and/or preventing in a subject diseases associated with bromodomains or bromodomain-containing proteins (e.g., proliferative diseases, cardiovascular diseases, viral infections, fibrotic diseases, metabolic diseases, endocrine diseases, and radiation poisoning). The compounds, pharmaceutical compositions, and kits are also useful for male contraception.
• AMINOMETHYLAMIDINE AND METHYLAMIDINE ANTIMICROBIAL COMPOUNDS
  申请人：BIOVERSYS AG

  公开号：US20210253589A1

  公开（公告）日：2021-08-19

  The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. In some embodiments, the present disclosure provides pyrrolo[2,3-d]pyrimidin-2-ones useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals.
• US7556858B2
  申请人：——

  公开号：US7556858B2

  公开（公告）日：2009-07-07
• US8933018B2
  申请人：——

  公开号：US8933018B2

  公开（公告）日：2015-01-13