p-tolyl(4-vinylphenyl)methanone | 24993-89-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: p-tolyl(4-vinylphenyl)methanone
• 英文别名: 4-(p-Methylbenzoyl)-styrol；(4-Ethenylphenyl)-(4-methylphenyl)methanone
• CAS: 24993-89-3
• 化学式: C₁₆H₁₄O
• 分子量: 222.287
• InChiKey: SIIVBAFKPXUAGD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-β-Bromethyl-4'-methylbenzophenon 以95%的产率得到
  参考文献：
  名称：

  POGOSYAN G. M., XIMIYA NEPREDELNYX SOEDIN., (EREVAN), 1979, HO 1, 159-179

  摘要：

  DOI：

文献信息

• Transition-metal-free carbonylation of aryl halides with arylboronic acids by utilizing stoichiometric CHCl₃ as the carbon monoxide-precursor
  作者：Fangning Xu、Dan Li、Wei Han

  DOI：10.1039/c9gc00598f

  日期：——

  Under transition-metal-free conditions, carbonylative Suzuki couplings of aryl halides with arylboronic acid using stoichiometric CHCl3 as the carbonyl source has been developed. The simple, efficient, and environmentally benign method was successfully applied to the synthesis of Fenofibric acid, naphthyl phenstatin, and carbon-13 labeled biaryl ketone.

  在无过渡金属的条件下，已开发出使用化学计量的CHCl 3作为羰基源的芳基卤化物与芳基硼酸的羰基Suzuki偶联反应。简单，高效，环境友好的方法已成功地用于合成非诺贝酸，萘酚他汀和碳13标记的联芳基酮。
• Process for the production of a transparent copolymer
  申请人：ATOFINA Research

  公开号：EP1408061A1

  公开（公告）日：2004-04-14

  The invention relates to a novel transparent block copolymer and its process for the manufacture. The process comprises a first partial killing of at least the living copolymeric species R-S1-B1-M with a multi-functional deactivation agent where S1 is a monovinyl-substitued aromatic homopolymer, B1 is a conjugated diene homopolymer, M is an alkali metal and R an alkyl (RM being an initiator) and further comprises a second total deactivation of at least the living tapered block copolymeric species R-S1-B1-B2/S2-M (obtained by adding a feed B2/S2 to the reaction medium) by a mono-functional deactivation agent (the terminating agent).

  本发明涉及一种新型透明嵌段共聚物及其制造工艺。该工艺包括至少用多功能失活剂对活体共聚物 R-S1-B1-M 进行第一次部分杀灭，其中 S1 是单乙烯基取代芳香族均聚物，B1 是共轭二烯均聚物，M 是碱金属，R 是烷基（RM 是引发剂）、M 是碱金属，R 是烷基（RM 是引发剂），还包括用单官能团失活剂（终止剂）对至少活的锥形嵌段共聚物 R-S1-B1-B2/S2-M（通过向反应介质中加入进料 B2/S2）进行第二次完全失活。
• Responsive microgel and methods related thereto
  申请人：——

  公开号：US20030152623A1

  公开（公告）日：2003-08-14

  A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic conditions) comprised of an ionizable network of covalently cross-linked homopolymeric ionizable monomers wherein the ionizable network is covalently attached to an amphiphilic copolymer to form a plurality of ‘dangling chains’ and wherein the ‘dangling chains’ of amphiphilic copolymer form immobile micelle-like aggregates in aqueous solution. A responsive microgel is further provided that comprises at least one therapeutic entity and delivers a substantially linear and sustained release of the therapeutic entity under physiological conditions.

  本发明提供了一种响应型微凝胶，该微凝胶可对选自由温度、pH 值和离子条件组成的组中的一种或多种水性条件的变化作出体积上和可逆的响应、和离子条件）组成的共价交联均聚可离子化单体的可离子化网络，其中可离子化网络与两性共聚物共价连接，形成多条 "悬链"，两性共聚物的 "悬链 "在水溶液中形成不动的胶束状聚集体。还提供了一种响应性微凝胶，它包含至少一种治疗实体，并能在生理条件下提供治疗实体的线性和持续释放。
• Transparent block copolymers and production thereof
  申请人：——

  公开号：US20040147682A1

  公开（公告）日：2004-07-29

  The invention relates to a novel transparent block copolymer and its process for the manufacture. The process comprises a first partial killing of at least the living copolymeric species R—S 1 —B 1 -M with a multi-functional deactivation agent where S 1 is a monovinyl-substitued aromatic homopolymer, B 1 is a conjugated diene homopolymer, M is an alkali metal and R an alkyl (RM being an initiator) and further comprises a second total deactivation of at least the living tapered block copolymeric species R—S 1 —B 1 —B 2 /S 2 -M (obtained by adding a feed B 2 /S 2 to the reaction medium) by a mono-functional deactivation agent (the terminating agent).

  本发明涉及一种新型透明嵌段共聚物及其制造工艺。该工艺包括首先部分杀死至少活的共聚物物种 R-S 1 -B 1 -M，其中 S 1 是单乙烯基取代芳香族均聚物，B 1 是共轭二烯均聚物，M 是碱金属，R 是烷基（RM 是引发剂），还包括至少对活体锥形嵌段共聚物 R-S 1 -B 1 -B 2 /S 2 -M（通过添加进料 B 2 /S 2 的单官能团失活剂（终止剂）。
• PRODUCTION OF ALKENYLBENZOPHENONE
  申请人：NIPPON PETROCHEMICALS COMPANY, LIMITED

  公开号：EP0422236B1

  公开（公告）日：1995-06-14