tris(allomaltolato)vanadium(III) monohydrate | 851853-87-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: tris(allomaltolato)vanadium(III) monohydrate
• CAS: 851853-87-7
• 化学式: C₁₈H₁₅O₉V*H₂O
• 分子量: 444.268
• InChiKey: OTXFAURXIUDASS-UHFFFAOYSA-K

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  别麦芽酚 、 oxovanadium(IV) sulfate 、 水 在 sodium dithionite 作用下， 以 水 为溶剂， 以75%的产率得到tris(allomaltolato)vanadium(III) monohydrate
  参考文献：
  名称：

  Coordination Chemistry and Insulin-Enhancing Behavior of Vanadium Complexes with Maltol C₆H₆O₃ Structural Isomers

  摘要：

  Syntheses of vanadium complexes using the naturally occurring ligands isomaltol (Hima) and allomaltol (Hama), as well as a newly synthesized, potentially tetradentate diaminodipyrone [H-2(en(ama)(2)], are reported. Complete characterization of the resulting compounds [trans-VO(ima)(2)(H2O), VO(ama)(2), V(ima)(3), V(ama)(3) and VO(en(ama)(2))], including X-ray crystallography analyses for trans-VO(ima)(2)(H2O) and V(ima)3, are presented herein. Potentiometric titrations (25 degrees C, / = 0.16 M NaCl) were used to measure stability constants in the V(IV)-Hima system; these data were compared to previous data collected on the V(IV)-L (L = Hma, Hama) systems. The in vivo efficacy of these compounds to lower the blood glucose levels of STZ-diabetic rats was tested; all but VO(en(ama)2) produced significant decreases in plasma glucose levels. The results were compared to those of the benchmark compound BMOV [VO(ma)(2), bis(maltolato)oxovanadium(IV)], a known insulin-enhancing agent.

  DOI：

  10.1021/ic048186g