2,2-bis-(4-hydroxy-3-methyl-phenyl)-hexane | 50628-54-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2-bis-(4-hydroxy-3-methyl-phenyl)-hexane
• 英文别名: 2,2-Bis-(4-hydroxy-3-methyl-phenyl)-hexan；4-[2-(4-Hydroxy-3-methylphenyl)hexan-2-yl]-2-methylphenol
• CAS: 50628-54-1
• 化学式: C₂₀H₂₆O₂
• 分子量: 298.425
• InChiKey: VEQBESIKKUEWCI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-己酮 、 邻甲酚 在 盐酸 作用下， 生成 2,2-bis-(4-hydroxy-3-methyl-phenyl)-hexane
  参考文献：
  名称：

  Campbell, Proceedings of the Royal Society of London. Series B, Biological sciences, 1940, vol. 129, p. 528,537

  摘要：

  DOI：

文献信息

• [EN] METHOD OF BISPHENOL MANUFACTURE<br/>[FR] PROCÉDÉ DE FABRICATION DE BISPHÉNOL
  申请人：SABIC GLOBAL TECHNOLOGIES BV

  公开号：WO2017100164A1

  公开（公告）日：2017-06-15

  An improved method of manufacture of a bisphenol comprises heating a monohydric phenol to a first temperature sufficient to melt the monohydric phenol; adding a carbonyl compound to 2.0-3.0 molar equivalents, based on the moles of carbonyl compound, of the monohydric phenol in the presence of catalytic amounts of an organosulfonic acid catalyst and a reaction promoter at a second temperature sufficient to maintain unreacted monohydric phenol in a molten state; increasing the temperature to a third temperature higher than the second temperature, and mixing for a time sufficient to produce the bisphenol in a yield of 80 to 100%, based on the amount of carbonyl compound; wherein mineral acids, Lewis acids, and ion exchange resins are not used. The method is applicable to the manufacture of 2,2-bis(3,5-dimethyl-4-hydroxyphenyl)propane, a useful intermediate for the manufacture of bifunctional poly(phenylene ether)s.

  一种改进的双酚制造方法包括将一种一元酚加热至足以使其熔化的第一温度；在存在催化量的有机磺酸催化剂和反应促进剂的情况下，向一元酚中加入2.0-3.0摩尔当量的羰基化合物，基于羰基化合物的摩尔数，在足以保持未反应的一元酚处于熔化状态的第二温度；将温度提高至高于第二温度的第三温度，并混合一段足以产生双酚的时间，其收率为80%至100%，基于羰基化合物的数量；其中不使用矿酸、路易斯酸和离子交换树脂。该方法适用于制造2,2-双(3,5-二甲基-4-羟基苯基)丙烷，这是制造双功能聚(苯醚)的有用中间体。
• POLY(ARYLENE ETHER) COPOLYMER
  申请人：SABIC Global Technologies B.V.

  公开号：EP3636692A1

  公开（公告）日：2020-04-15

  A poly(arylene ether) copolymer is the product of oxidative copolymerization of monomers including a monohydric phenol and a dihydric phenol of the formula wherein R3, R4, R5, and R6 are as defined herein. The poly(arylene ether) copolymer includes less than 0.1 weight percent of incorporated amine groups. A method of the manufacture of a poly(arylene ether) copolymer is also disclosed. A curable composition including the poly(arylene ether) copolymer and cured products derived therefrom are also described.

  聚芳基醚共聚物是单体氧化共聚的产物，单体包括式如下的一元酚和二元酚 其中 R3、R4、R5 和 R6 如本文所定义。该聚（芳基醚）共聚物包括小于 0.1 重量百分比的掺入胺基团。还公开了一种聚（芳基醚）共聚物的制造方法。还描述了一种包括聚（丙烯烯醚）共聚物的可固化组合物及其固化产品。
• POLY(ARYLENE ETHER) COPOLYMER, METHOD TO PREPARE THE SAME, AND ARTICLE DERIVED THEREFROM
  申请人：SHPP Global Technologies B.V.

  公开号：EP3919544A1

  公开（公告）日：2021-12-08

  A capped poly(arylene ether) copolymer includes a reactive end group, wherein the capped poly(arylene ether) copolymer is derived from an alkyl, aryl-phenol.

  一种封端聚（芳基醚）共聚物包括一个活性端基，其中封端聚（芳基醚）共聚物由烷基、芳基-苯酚衍生而来。
• CURABLE THERMOSETTING COMPOSITION INCLUDING POLY(ARYLENE ETHER) COPOLYMER
  申请人：SHPP Global Technologies B.V.

  公开号：EP3919545A1

  公开（公告）日：2021-12-08

  A curable thermosetting composition, comprising a capped poly(arylene ether) copolymer comprising a reactive end group, wherein the capped poly(arylene ether) copolymer is derived from an alkyl, aryl-phenol.

  一种可固化的热固性组合物，包含一种由活性末端基团组成的封端的聚（芳基醚）共聚物，其中封端的聚（芳基醚）共聚物由烷基、芳基-苯酚衍生而来。
• Method of bisphenol manufacture
  申请人：SABIC Global Technologies B.V.

  公开号：US10308579B2

  公开（公告）日：2019-06-04

  An improved method of manufacture of a bisphenol comprises heating a monohydric phenol to a first temperature sufficient to melt the monohydric phenol; adding a carbonyl compound to 2.0-3.0 molar equivalents, based on the moles of carbonyl compound, of the monohydric phenol in the presence of catalytic amounts of an organosulfonic acid catalyst and a reaction promoter at a second temperature sufficient to maintain unreacted monohydric phenol in a molten state; increasing the temperature to a third temperature higher than the second temperature, and mixing for a time sufficient to produce the bisphenol in a yield of 80 to 100%, based on the amount of carbonyl compound; wherein mineral acids, Lewis acids, and ion exchange resins are not used. The method is applicable to the manufacture of 2,2-bis(3,5-dimethyl-4-hydroxyphenyl)propane, a useful intermediate for the manufacture of bi-functional poly(phenylene ether)s.

  一种改进的双酚制造方法包括将一元苯酚加热到足以熔化一元苯酚的第一温度；将羰基化合物加入到 2.0-3.0摩尔当量（基于羰基化合物的摩尔数）的一水酚，在催化量的有机磺酸催化剂和反应促进剂的存在下，在足以使未反应的一水酚保持熔融状态的第二温度下进行；将温度升高至高于第二温度的第三温度，并混合足够长的时间，以生产出产率为80％至100％（基于羰基化合物的量）的双酚；其中不使用矿物酸、路易斯酸和离子交换树脂。该方法适用于制造 2,2-双（3,5-二甲基-4-羟基苯基）丙烷，它是制造双官能团聚亚苯基醚的有用中间体。