4-oxatricyclo<5,1,0,0>octane | 285-51-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环己烷
• 英文名称: 4-oxatricyclo<5,1,0,0>octane
• 英文别名: 4-Oxatricyclo[5.1.0.0(3,5)]octane；4-oxatricyclo[5.1.0.03,5]octane
• CAS: 285-51-8
• 化学式: C₇H₁₀O
• 分子量: 110.156
• InChiKey: SAKHFEFBWLXIEX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-oxatricyclo<5,1,0,0>octane 在 lithium diisopropyl amide 作用下， 以 吡啶 、 乙醚 、 正己烷 为溶剂， 反应 32.5h， 生成 (1,4,6)-4-acetoxybicyclo<4,1,0>hept-2-en-1-ene
  参考文献：
  名称：

  Banwell, Martin G.; Halton, Brian, Australian Journal of Chemistry, 1980, vol. 33, # 10, p. 2277 - 2290

  摘要：

  DOI：
• 作为产物：
  描述：

  3-norcarene 在 间氯过氧苯甲酸 作用下， 生成 4-oxatricyclo<5,1,0,0>octane
  参考文献：
  名称：

  在二铁加氧酶 AlkB 的烷烃羟基化过程中，笼子逃逸与成对重组竞争。

  摘要：

  Three structurally analogous radical clock substrates with a 100-fold span in their rearrangement rates are hydroxylated by the diiron oxygenase AlkB to afford similar amounts of rearranged and unrearranged products. Such a result is predicted by a mechanistic scheme by which radical rebound competes with cage escape of the geminate substrate radical. The results show that radical clocks can measure both the radical life-time and the kinetics of cage escape.

  DOI：

  10.1002/anie.200801184

文献信息

• HIGHER FUNCTIONAL POLYETHER CARBONATE POLYOLS OBTAINED USING BRANCHING MOLECULES
  申请人：COVESTRO DEUTSCHLAND AG

  公开号：US20160194444A1

  公开（公告）日：2016-07-07

  The present invention relates to a method for producing higher functional polyether carbonate polyols, said method preferably comprising the steps of ([alpha]) providing a DMC catalyst and: ([alpha][alpha]) a suspending agent that does contain any H-functional groups and/or ([alpha][beta]) an H-functional starter compound ([beta]) adding carbon dioxide and at least one alkylene oxide ([gamma]) adding carbon dioxide and at least two alkylene oxides, wherein these alkylene oxides can be the same as or different from the alkylene oxide or alkylene oxides added in step ([beta]), and ([delta]) adding carbon dioxide and at least one alkylene oxide, wherein this alkylene oxide or these alkylene oxides can be the same as or different from the alkylene oxides added in steps ([beta]) and ([gamma]), at least one of the alkylene oxides in step ([gamma]) having an epoxy functionality of >=2 and, in addition, in the case that no H-functional starter compound is provided in ([alpha]), step ([delta]) includes the addition of an H-functional starter compound.
• US9957354B2
  申请人：——

  公开号：US9957354B2

  公开（公告）日：2018-05-01
• Banwell, Martin G.; Halton, Brian, Australian Journal of Chemistry, 1980, vol. 33, # 10, p. 2277 - 2290
  作者：Banwell, Martin G.、Halton, Brian

  DOI：——

  日期：——
• Cage Escape Competes with Geminate Recombination during Alkane Hydroxylation by the Diiron Oxygenase AlkB
  作者：Rachel N. Austin、Kate Luddy、Karla Erickson、Marilla Pender‐Cudlip、Erin Bertrand、Dayi Deng、Ryan S. Buzdygon、Jan B. van Beilen、John T. Groves

  DOI：10.1002/anie.200801184

  日期：2008.6.27

  Three structurally analogous radical clock substrates with a 100-fold span in their rearrangement rates are hydroxylated by the diiron oxygenase AlkB to afford similar amounts of rearranged and unrearranged products. Such a result is predicted by a mechanistic scheme by which radical rebound competes with cage escape of the geminate substrate radical. The results show that radical clocks can measure both the radical life-time and the kinetics of cage escape.