E-β-(4-methyl)styrylgermatrane | 489432-96-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: E-β-(4-methyl)styrylgermatrane
• CAS: 489432-96-4；490020-95-6
• 化学式: C₁₅H₂₁GeNO₃
• 分子量: 335.927
• InChiKey: NZJGJJNLTDKQJJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  三乙醇胺 在 四(三苯基膦)钯 Et₃N 作用下， 以 四氢呋喃 、 乙醇 、 正己烷 、 甲苯 为溶剂， 生成 E-β-(4-methyl)styrylgermatrane
  参考文献：
  名称：

  One-Step Syntheses of Styryl Germatranes via Rhodium- or Palladium-Catalyzed Hydrogermylation of Arylacetylenes by HGe(OCH₂CH₂)₃N

  摘要：

  The addition of germatrane, HGe(OCH2-CH2)(3)N (1), to terminal acetylenes is catalyzed by [Cp*RhCl2](2) and yields styrylgermatranes The stereochemistry of the double bond can be controlled by the choice of solvent. In methylene chloride, (E)-beta-styrylgermatranes are the major products, whereas in toluene (Z)-styrylgermatranes are the major products. The addition is also catalyzed by Pd(PPh3)(4), giving (E)-beta-styrylgermatranes regardless of solvent.

  DOI：

  10.1021/om020714d

文献信息

• Palladium-Catalyzed Cross-Coupling Reactions of Allyl, Phenyl, Alkenyl, and Alkynyl Germatranes with Aryl Iodides
  作者：J. W. Faller、Roman G. Kultyshev

  DOI：10.1021/om020578c

  日期：2002.12.1

  The potential of using organogermatranes in palladium-catalyzed cross-coupling with aryl iodides has been investigated. We have found that organogermatranes are less reactive in this analogue of Stille coupling than trialkylorganostannanes; nevertheless activation by fluoride promotes the reaction. The hypervalent germanium species produced from the germatranes provide a more efficient and more easily handled reagent than trialkoxygermanium. analogues.