S-p-Tolyl-thiosulfat | 46132-99-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: S-p-Tolyl-thiosulfat
• 英文别名: 1-Methyl-4-sulfosulfanylbenzene
• CAS: 46132-99-4
• 化学式: C₇H₈O₃S₂
• 分子量: 204.271
• InChiKey: LEBKCOVLLMGBRO-UHFFFAOYSA-N

物化性质

• 密度：
  1.48±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  88
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  对甲苯磺酰氯 在 sodium sulfite 作用下， 生成 S-p-Tolyl-thiosulfat
  参考文献：
  名称：

  612.一些芳磺酰氯的反应

  摘要：

  DOI：

  10.1039/jr9600003063

文献信息

• NOVEL ORGANIC SULFUR COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER OR AN INFLAMMATORY DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT
  申请人：SOOKMYUNG WOMENS UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

  公开号：US20210300865A1

  公开（公告）日：2021-09-30

  A novel organic sulfur compound, a method for preparing the same, and a pharmaceutical composition for preventing or treating cancer or inflammatory diseases, containing the same as an active ingredient are provided. The novel organic sulfur compound is capable of excellently inhibiting histone deacetylated (HDAC) enzymes in a concentration of nanomolar or micromolar units and has been found to have an excellent effect against inflammatory diseases, and has been found to be capable of inhibiting the proliferation of cancer.

  提供一种新型有机硫化合物，一种制备该化合物的方法，以及一种包含该化合物作为活性成分的用于预防或治疗癌症或炎症性疾病的药物组合物。这种新型有机硫化合物能够在纳摩尔或微摩尔单位的浓度下出色地抑制组蛋白去乙酰化酶（HDAC），已发现对炎症性疾病具有出色的作用，并且已发现能够抑制癌症的增殖。
• [EN] TRIAZINANES POSSESSING THIOSULFONATE END-GROUPS AND METHODS OF MAKING THEM<br/>[FR] TRIAZINANES POSSÉDANT DES GROUPES À EXTRÉMITÉ THIOSULFONATE ET LEURS PROCÉDÉS DE FABRICATION
  申请人：FLEXSYS AMERICA LP

  公开号：WO2021216487A1

  公开（公告）日：2021-10-28

  The present invention is directed to compounds represented by the formula (I): wherein R1 comprises a hydrogen atom or an alkyl group having 1 to 2 carbon atoms. wherein R2 comprises an alkylene group, an arylene group, or a heterocyclic group. The three R2 groups may be the same or different. wherein A comprises an alkyl, an aryl, or an alkylaryl group. The three A groups may be the same or different.39

  本发明涉及由以下式（I）表示的化合物：其中R1包括一个氢原子或具有1至2个碳原子的烷基基团。其中R2包括一个烷基基团、芳基基团或杂环基团。三个R2基团可以相同也可以不同。其中A包括一个烷基、芳基或烷基芳基基团。三个A基团可以相同也可以不同。
• Compounds for protecting hydroxyls and methods for their use
  申请人：——

  公开号：US20020015961A1

  公开（公告）日：2002-02-07

  A hydrocarbyldithiomethyl-modified compound of the Formula: R 1 —O—CH 2 —S—S—R 2 or a salt thereof wherein R 1 is an organic molecule and R 2 is a hydrocarbyl is useful for protecting and/or blocking hydroxyl groups in organic molecules such as nucleotides. The hydrocarbyldithiomethyl-modified compounds can also be used for chemically synthesizing oligonucleotides and for sequencing nucleic acid compounds.

  一种Formula: R1-O-CH2-S-S-R2或其盐的羟烷基硫代甲基修饰化合物，其中R1是有机分子，R2是烃基，可用于保护和/或阻断核苷酸等有机分子中的羟基。这些羟烷基硫代甲基修饰化合物还可用于化学合成寡核苷酸和测序核酸化合物。
• Vulcanisable rubber composition and compounds useful as stabilising agents for rubber vulcanisates
  申请人：MONSANTO EUROPE S.A.

  公开号：EP0129527A2

  公开（公告）日：1984-12-27

  Additives tor rubber compositions, giving vulcanisates having improved retention of optimum physical properties, are compounds having the formula R-S-B-S-R where B is an organic bridging group and R is an electron-withdrawing group, for example CN, CCl3, a radical containing an activated methylene group linked to the sulphur atom or the enolic tautomer of a keto-activated methylene group. Also useful as stabilising agents are oligomeric analogues of such compounds.

  具有 R-S-B-S-R 式的化合物是橡胶组合物的添加剂，可使硫化胶更好地保持最佳物理性能，其中 B 是有机桥基，R 是抽电子基团，例如 CN、CCl3、含有与硫原子相连的活化亚甲基的自由基或酮活化亚甲基的烯醇同系物。 这类化合物的低聚类似物也可用作稳定剂。
• Substituted triazolopyrimidines and their use in light-sensitive photographic elements
  申请人：AGFA-GEVAERT naamloze vennootschap

  公开号：EP0190375A1

  公开（公告）日：1986-08-13

  Photographic element comprising a support and a silver halide emulsion layer comprising in said emulsion layer and/or in a water-permeable layer coated at the same side of the support as said emulsion layer a compound corresponding to the following general formula: wnerein: each of R1, R2, and R3, which may be the same or diffc can represent hydrogen, C1-C8alkyl, or Alk, - X - Alk2-. wherein: Alk, is C1-C8alkyl, which may be substituted, X is -0- or -S- , Alk2 is C1-C8alkylene, which may be substituted, and Y is a single bond, -0-, -S- , -CONH- , -SO2NH- , or -NHCONH-, R3 can alternatively represent C1-C8alkyl-thio, the C1-C8alkyl group of which can be substituted, at least one of R1, R2, and R3, however, being other than hydrogen and other than C1-C8alkyl. The invention disclosed includes compounds per se, which correspond to said general formula.

  摄影元件，包括一个支架和一个卤化银乳剂层，在所述乳剂层中和/或在与所述乳剂层位于支架同一侧的透水层中涂覆有与下式通式相对应的化合物： 其中，R1、R2 和 R3 可以相同或不同地代表氢、C1-C8 烷基或 Alk、- X - Alk2-： X为-0-或-S-，Alk2为C1-C8亚烷基，可被取代，Y为单键、-0-、-S-、-CONH-、-SO2NH-或-NHCONH-、 R3 也可以代表 C1-C8 烷硫基，其中的 C1-C8 烷基可以被取代。 基团可以被取代、 但 R1、R2 和 R3 中至少有一个不是 氢和 C1-C8 烷基以外。 所公开的本发明包括符合所述通式的化合物本身。