N,N-dimethyl-1-oxo-2,5-diphenyl-2,5-dihydro-1lambda5-phosphol-1-amine | 1198309-52-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N-dimethyl-1-oxo-2,5-diphenyl-2,5-dihydro-1lambda5-phosphol-1-amine
• 英文别名: N,N-dimethyl-1-oxo-2,5-diphenyl-2,5-dihydro-1λ5-phosphol-1-amine
• CAS: 1198309-52-2
• 化学式: C₁₈H₂₀NOP
• 分子量: 297.337
• InChiKey: ABAXNMRBYZYUBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N,N-dimethyl-1-oxo-2,5-diphenyl-2,5-dihydro-1lambda5-phosphol-1-amine 在 palladium 10% on activated carbon 、 氢气 作用下， 以 甲醇 为溶剂， 反应 65.0h， 以6 g的产率得到(rac)-1-(dimethylamino)-2,5-diphenylphospholane 1-oxide
  参考文献：
  名称：

  Ambient Temperature Hydrophosphination of Internal, Unactivated Alkynes and Allenyl Phosphineoxides with Phosphine Borane Complexes

  摘要：

  Phosphine boranes have been found to hydrophosphinate internal, unactivated alkynes at room temperature under basic conditions without the need for catalysts or radical initiators, The use of air-sensitive secondary phosphines is avoided in this facile process. Broad scope in both the phosphine borane and alkyne partners leads to excellent diversity in the phosphine products. Asymmetric hydrogenation of these species then provides one of the shortest possible routes to chiral monodentate phosphines, Hydrophosphination of allenyl phosphine oxides under similar conditions followed by hydrogenation of the exomethylene moiety yields a wide variety of bis-phosphine derivatives.

  DOI：

  10.1021/ol9022547
• 作为产物：
  描述：

  二甲基氯化磷胺 、 1,4-二苯基1,3-丁二烯 在 aluminum (III) chloride 、 ethylene diamine tetraacetic acid tetrasodium salt 、 碳酸氢钠 作用下， 以 二氯甲烷 为溶剂， 反应 0.42h， 生成 N,N-dimethyl-1-oxo-2,5-diphenyl-2,5-dihydro-1lambda5-phosphol-1-amine
  参考文献：
  名称：

  Ambient Temperature Hydrophosphination of Internal, Unactivated Alkynes and Allenyl Phosphineoxides with Phosphine Borane Complexes

  摘要：

  Phosphine boranes have been found to hydrophosphinate internal, unactivated alkynes at room temperature under basic conditions without the need for catalysts or radical initiators, The use of air-sensitive secondary phosphines is avoided in this facile process. Broad scope in both the phosphine borane and alkyne partners leads to excellent diversity in the phosphine products. Asymmetric hydrogenation of these species then provides one of the shortest possible routes to chiral monodentate phosphines, Hydrophosphination of allenyl phosphine oxides under similar conditions followed by hydrogenation of the exomethylene moiety yields a wide variety of bis-phosphine derivatives.

  DOI：

  10.1021/ol9022547

文献信息

• Chromium complex and catalyst therefrom
  申请人：Dow Global Technologies LLC

  公开号：US10207262B2

  公开（公告）日：2019-02-19

  The invention relates to oligomerization of olefins, such as ethylene, to higher olefins, such as a mixture of 1-hexene and 1-octene, using a catalyst system that comprises a) a source of chromium b) one or more activators and c) a phosphacycle-containing ligating compound. Additionally, the invention relates to a phosphacycle-containing ligating compound and a process for making said compound.

  本发明涉及使用催化剂体系将烯烃（如乙烯）低聚为高碳烯烃（如 1-己烯和 1-辛烯的混合物），该催化剂体系包括 a) 铬源 b) 一种或多种活化剂和 c) 含磷环连接化合物。此外，本发明还涉及一种含磷环的连接化合物和制造所述化合物的工艺。
• Phosphacycle compound and process for production thereof
  申请人：Dow Global Technologies LLC

  公开号：US10357764B2

  公开（公告）日：2019-07-23

  The invention relates to oligomerization of olefins, such as ethylene, to higher olefins, such as a mixture of 1-hexene and 1-octene, using a catalyst system that comprises a) a source of chromium b) one or more activators and c) a phosphacycle-containing ligating compound. Additionally, the invention relates to a phosphacycle-containing ligating compound and a process for making said compound.

  本发明涉及使用催化剂体系将烯烃（如乙烯）低聚为高碳烯烃（如 1-己烯和 1-辛烯的混合物），该催化剂体系包括 a) 铬源 b) 一种或多种活化剂和 c) 含磷环连接化合物。此外，本发明还涉及一种含磷环的连接化合物和制造所述化合物的工艺。
• Process for oligomerization
  申请人：Dow Global Technologies LLC

  公开号：US10376869B2

  公开（公告）日：2019-08-13

  The invention relates to oligomerization of olefins, such as ethylene, to higher olefins, such as a mixture of 1-hexene and 1-octene, using a catalyst system that comprises a) a source of chromium b) one or more activators and c) a phosphacycle-containing ligating compound. Additionally, the invention relates to a phosphacycle-containing ligating compound and a process for making said compound.

  本发明涉及使用催化剂体系将烯烃（如乙烯）低聚为高碳烯烃（如 1-己烯和 1-辛烯的混合物），该催化剂体系包括 a) 铬源 b) 一种或多种活化剂和 c) 含磷环连接化合物。此外，本发明还涉及一种含磷环的连接化合物和制造所述化合物的工艺。
• CHROMIUM COMPLEX AND CATALYST THEREFROM
  申请人：Dow Global Technologies LLC

  公开号：US20180071725A1

  公开（公告）日：2018-03-15

  The invention relates to oligomerization of olefins, such as ethylene, to higher olefins, such as a mixture of 1-hexene and 1-octene, using a catalyst system that comprises a) a source of chromium b) one or more activators and c) a phosphacycle-containing ligating compound. Additionally, the invention relates to a phosphacycle-containing ligating compound and a process for making said compound.
• PROCESS FOR OLIGOMERIZATION
  申请人：Dow Global Technologies LLC

  公开号：US20180154344A1

  公开（公告）日：2018-06-07

  The invention relates to oligomerization of olefins, such as ethylene, to higher olefins, such as a mixture of 1-hexene and 1-octene, using a catalyst system that comprises a) a source of chromium b) one or more activators and c) a phosphacycle-containing ligating compound. Additionally, the invention relates to a phosphacycle-containing ligating compound and a process for making said compound.