(iodo-nitro-methyl)-benzene | 876493-96-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (iodo-nitro-methyl)-benzene
• 英文别名: (Jod-nitro-methyl)-benzol；Nitrobenzyl iodide；[iodo(nitro)methyl]benzene
• CAS: 876493-96-8
• 化学式: C₇H₆INO₂
• 分子量: 263.035
• InChiKey: KJNXOXPIKODLEL-UHFFFAOYSA-N

物化性质

• 沸点：
  264.5±33.0 °C(Predicted)
• 密度：
  1.904±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (iodo-nitro-methyl)-benzene 、 苯肼 生成 (α-nitro-benzylidene)-phenyl-hydrazine
  参考文献：
  名称：

  Nenitzescu; Isacescu, Buletinul Societatii de Chimie din Romania, 1931, vol. 13, p. 89,90

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 碘 、 potassium iodide 作用下， 生成 (iodo-nitro-methyl)-benzene
  参考文献：
  名称：

  Nenitzescu; Isacescu, Chemische Berichte, 1930, vol. 63, p. 2484,2493

  摘要：

  DOI：

文献信息

• 2,6-DIOXO-3-DEUTERO-PIPERDIN-3-YL-ISOINDOLINE COMPOUNDS
  申请人：DeWitt Sheila

  公开号：US20120252844A1

  公开（公告）日：2012-10-04

  The present application describes 2-(2′,6′-dioxo-3′-deutero-piperidin-3′-yl)isoindoles, deuterated derivatives thereof, stereoisomers thereof, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.

  本申请描述了2-(2′，6′-二氧代-3′-氘代-哌啶-3′-基)异吲哚，其氘代衍生物，立体异构体，药学上可接受的盐形式以及使用它们治疗的方法。
• 2',6'-DIOXO-3'-DEUTERO-PIPERDIN-3-YL-ISOINDOLINE COMPOUNDS
  申请人：DeuteRx, LLC

  公开号：US20160002202A1

  公开（公告）日：2016-01-07

  The present application describes 2-(2′,6′-dioxo-3′-deutero-piperidin-3′-yl)isoindoles, deuterated derivatives thereof, stereoisomers thereof, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.

  本申请描述了2-(2′,6′-二氧代-3′-氘代哌啶-3′-基)异吲哚，其氘代衍生物，其立体异构体，其药学上可接受的盐形式以及使用它们治疗的方法。
• PROCESS FOR FRIEDEL-CRAFTS REACTION, AND CATALYST THEREFORE
  申请人：Fujian Yongjing Technology Co., Ltd.

  公开号：EP3696157A1

  公开（公告）日：2020-08-19

  The invention relates to a new process for the manufacture or synthesis, respectively, of acylated or alkylated aryl compounds, for example, acylated or alkylated benzenes, by the so-called Friedel-Crafts reaction, and a new catalyst therefore.. The present invention particularly pertains to a novel environmentally friendly process for the synthesis of the said acylated or alkylated compounds Friedel-Crafts reaction.

  本发明涉及一种通过所谓的弗里德尔-卡夫斯反应分别制造或合成酰化或烷化芳基化合物（例如酰化或烷化苯）的新工艺，以及因此而产生的一种新催化剂。本发明尤其涉及一种新型环保工艺，用于合成上述酰化或烷基化化合物的弗里德尔-卡夫斯反应。
• Process for Friedel-Crafts Reaction, and Catalyst Therefore
  申请人：Fujian Yongjing Technology Co., Ltd.

  公开号：US20200262775A1

  公开（公告）日：2020-08-20

  The invention relates to a new process for the manufacture of fluoroaryl compounds and derivatives thereof, in particular of fluorobenzenes and derivatives thereof, and especially wherein said manufacture relates to an environmentally friendly production of the said compounds. Thus, the present invention overcomes the disadvantages of the prior art processes, and in a surprisingly simple and beneficial manner, and as compared to the prior art processes, in particular, the invention provides a more efficient and energy saving processes, and also provides a more environmentally friendly process, for the manufacture of nuclear fluorinated aromatics, and preferably of nuclear fluorinated fluorobenzenes. Accordingly, in one aspect of the invention, an industrially beneficial process for preparing fluorobenzenes from halobenzene precursors using HF to form hydrogen halide is provided by the present invention. A beneficial and surprisingly simple use of chlorobenzene as an industrially interesting starting material in the manufacture of fluorobenzene is provided.
• US3944553A
  申请人：——

  公开号：US3944553A

  公开（公告）日：1976-03-16