4-methyl-5-phenylpentanal | 57919-02-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methyl-5-phenylpentanal
• CAS: 57919-02-5
• 化学式: C₁₂H₁₆O
• 分子量: 176.258
• InChiKey: CKSFQAPUASVEIT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (2-硝基丙基)苯 在 偶氮二异丁腈 、 三正丁基氢锡 、 三乙胺 作用下， 以 乙腈 、 苯 为溶剂， 反应 2.0h， 生成 4-methyl-5-phenylpentanal
  参考文献：
  名称：

  New synthetic methods. Conjugate addition of alkyl groups to electron deficient olefins with nitroalkanes as alkyl anion equivalents

  摘要：

  DOI：

  10.1021/jo00220a003

文献信息

• [EN] AMBER ODORANT<br/>[FR] AMBRE ODORANTE
  申请人：FIRMENICH & CIE

  公开号：WO2020239682A1

  公开（公告）日：2020-12-03

  The present invention concerns compound of formula (I) in the form of any one of its stereoisomers or as a mixture thereof, and wherein R1 represents a hydrogen atom, a C1-3 alkyl group or C2-3 alkenyl group; X represents an oxygen atom when R2 represents a C1-4 alkyl group or C2-4 alkenyl group or X represents a CH2-O group when R2 represents a C2-4 alkenyl group or a MeC=O group. The use as a perfuming ingredient of the invention's compound and the invention's compound as part of a perfuming composition or of a perfuming consumer product are also part of the present invention.

  本发明涉及式（I）的化合物，其为其立体异构体之一或其混合物的形式，其中R1代表氢原子、C1-3烷基或C2-3烯基；X代表氧原子，当R2代表C1-4烷基或C2-4烯基时，或X代表CH2-O基团，当R2代表C2-4烯基或MeC=O基团时。本发明的化合物作为香料成分的用途，以及本发明的化合物作为香料组合物或香料消费产品的一部分，也属于本发明的范围。
• Benzimidazolinone derivatives
  申请人：YAMANOUCHI PHARMACEUTICAL CO. LTD.

  公开号：EP0454330A1

  公开（公告）日：1991-10-30

  Benzimidazolinone derivatives of the general formula (I): wherein R1, R2 and R3, which may be the same or different, each is a hydrogen or halogen atom or a lower alkyl, halo-lower alkyl, hydroxy-lower alkyl, hydroxyl, lower alkoxy, aryloxy, acyl, cyano, carboxyl, a lower alkoxycarbonyl, carbamoyl, nitro or nitrogen-containing 5- or 6-membered heterocyclic group; A is an ethylene group which may optionally have at least one branch ; R4 and R5, which may be the same or different, each is a lower alkyl group or R4 and R5, together with the adjacent nitrogen atom, represent a pyrrolidinyl, piperidino or a morpholino group provided that when is a piperidino or diethylamino group, at least one of R1, R2 and R3 is other than a hydrogen atom, or pharmaceutically acceptable salts thereof, methods of producing the same and pharmaceutical compositions containing the same are disclosed. Pharmacologically, the above compounds (I) have pulmonary surfactant secretion promoting activity.

  通式(I)的苯并咪唑啉酮衍生物： 其中 R1、R2 和 R3 可以相同或不同，各自为氢原子或卤素原子或低级烷基、卤代低级烷基、羟基低级烷基、羟基、低级烷氧基、芳氧基、酰基、氰基、羧基、低级烷氧基羰基、氨基甲酰基、硝基或含氮的 5 或 6 元杂环基团；R4 和 R5（可以相同或不同）各自是低级烷基，或 R4 和 R5 与相邻的氮原子一起代表吡咯烷基、哌啶基或吗啉基，条件是 公开了 R1、R2 和 R3 中至少一个不是氢原子的哌啶或二乙胺基团，或其药学上可接受的盐类，以及生产上述化合物和含有上述化合物的药物组合物的方法。在药理学上，上述化合物（I）具有促进肺表面活性物质分泌的活性。
• Amber odorant
  申请人：FIRMENICH SA

  公开号：US10889558B2

  公开（公告）日：2021-01-12

  Described herein is a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and where the Q group represents a —CH═CH—CH3 group or a —C≡C—CH3 group. Also described herein is a method of using a compound of formula (I), the method including using the compound of formula (I) as part of a perfuming composition or as part of a perfumed consumer product.

  这里描述的是式 (I) 的化合物 以其任意一种立体异构体或其混合物的形式，其中 Q 基团代表 -CH═CH-CH3 基团或 -C≡C- 基团。本文还描述了一种使用式(I)化合物的方法，该方法包括将式(I)化合物用作香水组合物的一部分或用作香味消费品的一部分。
• Use of ambrocenide® for intensifying a lily of the valley scent
  申请人：SYMRISE AG

  公开号：US11091723B2

  公开（公告）日：2021-08-17

  The present invention primarily relates to the use of one or more stereoisomers of the compound of formula (I) as described herein for modifying and/or enhancing the olfactory impression of one or more fragrances with a lily of the valley scent. The invention further relates to a new mixture comprising or consisting of one or more stereoisomers of the compound of formula (I) as described herein and two or more stereoisomers of the compound of formula (II) as described herein with a weight ratio of the stereoisomers of the compounds of formula (II) as described herein, fragrance compositions comprising or consisting of a mixture as described herein, perfumed products containing mixtures or fragrance composition as described herein, and a process for modifying and/or enhancing the lily of the valley scent of a compound of formula (II) as described herein, respectively for preparing a perfumed product as described herein.

  本发明主要涉及本文所述的式(I)化合物的一种或多种立体异构体用于改变和/或增强一种或多种具有铃兰香味的香水的嗅觉印象。本发明还涉及一种新混合物，该混合物包含或由一种或多种本文所述的式 (I) 化合物的立体异构体和两种或多种本文所述的式 (II) 化合物的立体异构体组成，其中式 (II) 化合物的立体异构体的重量比如本文所述、包含或由本文所述混合物组成的香料组合物、含有本文所述混合物或香料组合物的香水产品，以及分别用于制备本文所述香水产品的修改和/或增强本文所述式（II）化合物的铃兰香味的工艺。
• ONO, NOBORU;KAMIMURA, AKIO;MIYAKE, HIDEYOSHI;HAMAMOTO, ISAMI;KAJI, ARITSU+, J. ORG. CHEM., 1985, 50, N 20, 3692-3698
  作者：ONO, NOBORU、KAMIMURA, AKIO、MIYAKE, HIDEYOSHI、HAMAMOTO, ISAMI、KAJI, ARITSU+

  DOI：——

  日期：——