2,6-di-tert-butyl-3-methylanisole | 1208459-36-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,6-di-tert-butyl-3-methylanisole
• 英文别名: 1,3-Ditert-butyl-2-methoxy-4-methylbenzene
• CAS: 1208459-36-2
• 化学式: C₁₆H₂₆O
• 分子量: 234.382
• InChiKey: PRRCEJYZGGVODI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,6-di-tert-butyl-3-methylanisole 在 碘 、 silver trifluoroacetate 作用下， 以 氯仿 为溶剂， 反应 0.25h， 以100%的产率得到2,6-di-tert-butyl-4-iodo-3-methylanisole
  参考文献：
  名称：

  Syntheses of extreme sterically hindered 4-methoxyboronic acids

  摘要：

  4-Iodoanisoles 3a,b, 3d and 4-bromoanisoles 4a-d were readily obtained. An extreme steric hindrance precluded obtaining 3c. Catalytic borylation of 3a,b, 3d followed by hydrolysis of boronic ester 26a,b, 26d easily provided the boronic acids 5a,b, 5d. Compounds Sa and 5d were also synthesised, starting from 4a and 4d, by halogen/metal exchange. Because of a too important steric hindrance, this last reaction failed with 4c and 4b led to the unexpected but stable boronic ester 6. The final obtaining of 5b required a strongly basic hydrolysis with heating. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.11.103
• 作为产物：
  描述：

  3-methyl-2,6-bis[2-(2-formylpropyl)]anisole 在 一水合肼 、 potassium hydroxide 作用下， 以 二乙二醇 为溶剂， 以58%的产率得到2,6-di-tert-butyl-3-methylanisole
  参考文献：
  名称：

  Syntheses of extreme sterically hindered 4-methoxyboronic acids

  摘要：

  4-Iodoanisoles 3a,b, 3d and 4-bromoanisoles 4a-d were readily obtained. An extreme steric hindrance precluded obtaining 3c. Catalytic borylation of 3a,b, 3d followed by hydrolysis of boronic ester 26a,b, 26d easily provided the boronic acids 5a,b, 5d. Compounds Sa and 5d were also synthesised, starting from 4a and 4d, by halogen/metal exchange. Because of a too important steric hindrance, this last reaction failed with 4c and 4b led to the unexpected but stable boronic ester 6. The final obtaining of 5b required a strongly basic hydrolysis with heating. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.11.103

文献信息

• [EN] BRIDGED BIS(INDENYL) TRANSITIONAL METAL COMPLEXES, PRODUCTION, AND USE THEREOF<br/>[FR] COMPLEXES DE MÉTAL DE TRANSITION BIS(INDÉNYLE) PONTÉS, PRODUCTION ET UTILISATION DE CEUX-CI
  申请人：EXXONMOBIL CHEM PATENTS INC

  公开号：WO2015095188A1

  公开（公告）日：2015-06-25

  The invention relates to a novel group bridged metallocene transition metal complexes, wherein the complex includes at least one indenyl ligand substituted at the 4- position with a phenyl group, the 4-phenyl group being preferably substituted at the 3 ', 4', and 5' positions with particular combinations of substituents, particularly wherein the 4'- substituent is a group of the formula (XR'n)-, wherein X is a Group 14-17 heteroatom having an atomic weight of 13 to 79 and R' is one of a hydrogen atom, halogen atom, a C1-C10 alkyl group, or a C6-C10 aryl group and n is 0, 1, 2, or 3. Catalyst systems including the transition metal complex, polymerization processes using the transition metal complex, and polymers made using the transition metal complex are also described.

  该发明涉及一种新型的桥联茂金属过渡金属配合物，其中该配合物包括至少一种在4-位置被苯基取代的茚基配体，所述的4-苯基在3'、4'和5'位置上最好被特定组合的取代基取代，特别是其中4'-取代基是一个具有化学式(XR'n)-的基团，其中X是具有原子量13至79的14-17族杂原子，R'是氢原子、卤原子、C1-C10烷基或C6-C10芳基中的一种，n为0、1、2或3。还描述了包括过渡金属配合物的催化剂体系、使用过渡金属配合物的聚合工艺以及使用过渡金属配合物制备的聚合物。
• BRIDGED BIS(INDENYL) TRANSITIONAL METAL COMPLEXES, PRODUCTION, AND USE THEREOF
  申请人：ExxonMobil Chemical Patents Inc.

  公开号：EP3083649A1

  公开（公告）日：2016-10-26