bis(2,3-dihydroxypropyl) (1R,2S,3R,4S)-7-oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate | 1134938-19-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: bis(2,3-dihydroxypropyl) (1R,2S,3R,4S)-7-oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate
• CAS: 1134938-19-4
• 化学式: C₁₄H₂₀O₉
• 分子量: 332.307
• InChiKey: JCQDXFPMKSNTSI-QSTBHEHHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.7
• 重原子数：
  23
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  143
• 氢给体数：
  4
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride 在 甲醇 、 4-二甲氨基吡啶 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 61.0h， 生成 bis(2,3-dihydroxypropyl) (1R,2S,3R,4S)-7-oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate
  参考文献：
  名称：

  Hydrogels Based on Living Ring-Opening Metathesis Polymerization

  摘要：

  Living ring opening metathesis polymerization (ROMP) of a hydrophilic norbornene monomer (M4) was performed successfully in air at room temperature using Grubbs third generation (G3) catalyst as the initiator ROMP was then used to copolymerize M4 with a hydrophilic difunctional norbornene cross-linker to develop a rapid and efficient method for preparing hydrogels Although intramolecular cyclization was observed under dilute conditions, the critical gelation behavior was found to agree with the mean-field theory of Flory and Stockmayer (FS theory) more consistently than that of conventional free radical polymerization systems By changing the length of the primary polymer chains, the initial molar ratio between monomer and cross-linker and the length of the cross linker, the equilibrium swelling ratio and the corresponding mechanical properties of the resultant hydrogels were manipulated across a broad range

  DOI：

  10.1021/ma101950f

文献信息

• Water-Soluble and Water-Insoluble, Ring Opening Metathesis Polymerization Products, Monomers and Related Methods
  申请人：Tew Gregory N.

  公开号：US20090082524A1

  公开（公告）日：2009-03-26

  The invention provides certain novel water-soluble and water-insoluble monomers for ring opening metathesis polymerization and novel polymers, compositions and products, and related methods thereof.

  这项发明提供了用于环氧烯烃开环重聚合的某些新型水溶性和不溶性单体，以及新型聚合物、组合物和产品，以及相关方法。
• US8329927B2
  申请人：——

  公开号：US8329927B2

  公开（公告）日：2012-12-11
• Hydrogels Based on Living Ring-Opening Metathesis Polymerization
  作者：Ke Zhang、Jun Cui、Melissa Lackey、Gregory N. Tew

  DOI：10.1021/ma101950f

  日期：2010.12.28

  Living ring opening metathesis polymerization (ROMP) of a hydrophilic norbornene monomer (M4) was performed successfully in air at room temperature using Grubbs third generation (G3) catalyst as the initiator ROMP was then used to copolymerize M4 with a hydrophilic difunctional norbornene cross-linker to develop a rapid and efficient method for preparing hydrogels Although intramolecular cyclization was observed under dilute conditions, the critical gelation behavior was found to agree with the mean-field theory of Flory and Stockmayer (FS theory) more consistently than that of conventional free radical polymerization systems By changing the length of the primary polymer chains, the initial molar ratio between monomer and cross-linker and the length of the cross linker, the equilibrium swelling ratio and the corresponding mechanical properties of the resultant hydrogels were manipulated across a broad range