| 63520-74-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 63520-74-1
• 化学式: C₈H₇ClMg
• 分子量: 162.902
• InChiKey: FOLHKANYGBXVCK-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  2.52
• 重原子数：
  10.0
• 可旋转键数：
  2.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  在 N,N’-diphenyl-p-benzoquinonediimine 作用下， 以 四氢呋喃 为溶剂， 反应 0.5h， 生成 1,4-二苯基-1,3丁二烯 、 1-[(1E,3Z)-4-苯基-1,3-丁二烯基]苯
  参考文献：
  名称：

  奎宁二胺诱导的有机镁试剂的氧化偶联。

  摘要：

  Ñ，Ñ N'-二苯基p -benzoquinonediimine，聚苯胺的氧化还原活性单元，有效地引起的各种芳基-和乙烯基的试剂的氧化自偶联在抑制副反应，如1,2-或1,4-加成反应。

  DOI：

  10.1002/chem.201301993

文献信息

• Arylation, Alkenylation, and Alkylation of 2-Halopyridine <i>N</i>-Oxides with Grignard Reagents: A Solution to the Problem of C2/C6 Regioselective Functionalization of Pyridine Derivatives
  作者：Song Zhang、Lian-Yan Liao、Fang Zhang、Xin-Fang Duan

  DOI：10.1021/jo302511s

  日期：2013.3.15

  alkenylation, and alkylation of functionalized 2-halopyridine N-oxides with various Grignard reagents was developed. It represented a highly efficient and selective C–H bond functionalization of pyridine derivatives in the presence of reactive C–Cl or C–Br bonds. Using Cl or Br as a blocking group, C2/C6 site-controllable functionalization of pyridine derivatives has been achieved. Various pyridine compounds

  开发了各种格氏试剂的简便芳基化，烯基化和烷基化的功能化的2-卤代吡啶N-氧化物。它代表了在存在反应性C–Cl或C–Br键的情况下吡啶衍生物的高效C–H键选择性官能化。使用Cl或Br作为封闭基团，已经实现了吡啶衍生物的C2 / C6位点可控的官能化。如Onychine，dielsine和PARP-1抑制剂GPI 16539的总合成所示，可以制备各种吡啶化合物。
• Catalytic component for polymerization of alpha-olefin and method for homo-or co-polymerization of alpha-olefin
  申请人：TOYO STAUFFER CHEMICAL CO. LTD.

  公开号：EP0067417A2

  公开（公告）日：1982-12-22

  A catalytic component for polymerization of an α-0lefin is prepared by allowing an organo-magnesium compound expressed by the generic formula of RMgX (wherein R represents a hydrocarbon group having 1 to 20 carbon atoms and X a halogen atom or a hydrocarbon group having 1 to 20 carbon atoms) to react with carbon tetrahalide in the presence of an electron donor compound to obtain a solid product; by treating the solid product with phenols at 90 to 180°C; and by further treating the phenol treated solid with a halogenated titanium compound. Homo- or co-polymerization of an a-olefin is carried out in the presence of a catalyst composition consisting of the catalytic component thus prepared and an organo-aluminum compound.

  一种用于α-0烯烃聚合的催化组分的制备方法是：使通式为RMgX的有机镁化合物（其中R代表具有1至20个碳原子的烃基，X代表卤素原子或具有1至20个碳原子的烃基）在电子供体化合物存在下与四卤化碳反应，得到固体产物；在90至180℃下用苯酚处理固体产物；再用卤化钛化合物进一步处理经苯酚处理的固体。在由由此制备的催化组分和有机铝化合物组成的催化剂组合物存在下，进行 a- 烯烃的均聚或共聚。
• Process for producing a catalyst component used for the polymerization of alpha-olefins
  申请人：TOYO STAUFFER CHEMICAL CO. LTD.

  公开号：EP0102503A2

  公开（公告）日：1984-03-14

  A process for producing a catalyst component used for the polymerization of an α-olefin comprising treating a solid product which is obtained by reacting an organomagnesium compound with a halogenation agent in the presence of an electron donor compound, with a mixture of a halogenated silicon compound and a titanium compound, which has particle size abundant in uniformity, a good flowability and in addition a high polymerization activity and yield ratio of stereo-specific polymers.

  一种生产用于α-烯烃聚合的催化剂组分的工艺，包括将有机镁化合物与卤化剂在电子供体化合物存在下反应得到的固体产物与卤化硅化合物和钛化合物的混合物进行处理，该混合物粒度均匀，流动性好，而且具有较高的聚合活性和立体特异性聚合物的产率。
• Gold and Brønsted Acid Catalyzed Spirocyclization of 2- and 3-Indolyl-Tethered 1,4-Enyne Acetates to Spiro[4,<i>n</i>]alkyl[<i>b</i>]indoles
  作者：Xiaoyu Chen、Corentin Antoine Baratay、Maddison Elizabeth Mark、Xinfang Xu、Philip Wai Hong Chan

  DOI：10.1021/acs.orglett.0c00929

  日期：2020.4.3

  A synthetic method to prepare spiro[4,n]alkyl[b]indoles (n = 4-6) efficiently that relies on the gold(I) and Bronsted acid mediated spirocyclization of 2- and 3-indolyl-tethered 1,4-enyne acetates at room temperature and open to air is described.
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Sn: Org.Verb.2, 1.1.2.15.4, page 386 - 396
  作者：

  DOI：——

  日期：——