2-aniline-3-hydroxypyridine | 92755-42-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-aniline-3-hydroxypyridine
• 英文别名: 2-(phenylamino)pyridine-3-ol；2-anilinopyridin-3-ol
• CAS: 92755-42-5
• 化学式: C₁₁H₁₀N₂O
• 分子量: 186.213
• InChiKey: ONVUKMIOINZASU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  45.2
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-methoxy-N-phenylpyridin-2-amine 在 盐酸 作用下， 生成 2-aniline-3-hydroxypyridine
  参考文献：
  名称：

  THIOAZOLE AND OXAZOLE CARBENE METAL COMPLEXES AS PHOSPHORESCENT OLED MATERIALS

  摘要：

  本发明提供了一种包含杂环卡宾配体的化合物。特别地，氧唑或噻唑卡宾被用来代替传统的咪唑卡宾。这些化合物可用于有机发光二极管（OLED）中，以提供具有改善性能（如稳定性和颜色调节）的设备。此外，本发明还提供了一种新的合成杂环卡宾金属配合物的方法。

  公开号：

  US20120212126A1

文献信息

• ANTI-INFLAMMATORY COMPOUND HAVING INHIBITORY ACTIVITY AGAINST MULTIPLE TYROSINE KINASES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
  申请人：Yang Beom-Seok

  公开号：US20130072482A1

  公开（公告）日：2013-03-21

  The present invention is for the anti-inflammatory compounds that have an inhibitory activity against protein tyrosine kinases and their pharmaceutical composition(s) containing the compound as the active ingredient. Since the compounds of the present invention can inhibit multiple protein kinases associated with inflammatory diseases and immune disorders, they are useful for their prevention or treatment.

  本发明涉及具有抑制蛋白酪氨酸激酶活性的抗炎化合物及其含有该化合物作为活性成分的药物组合物。由于本发明的化合物可以抑制与炎症性疾病和免疫紊乱相关的多种蛋白激酶，因此它们对于预防或治疗这些疾病是有用的。
• Thioazole and oxazole carbene metal complexes as phosphorescent OLED materials
  申请人：Tsai Jui-Yi

  公开号：US09005772B2

  公开（公告）日：2015-04-14

  Compounds are provided that comprise a heterocyclic carbene ligand. In particular, an oxazole or a thioazole carbene are used in place of the traditional imidazole carbene. These compounds may be used in OLEDs to provide devices having improved properties, such as stability and color-tuning. Additionally, a novel methodology to synthesize heterocyclic carbene metal complexes is provided.

  提供了包含杂环卡宾配体的化合物。特别地，氧唑或噻唑卡宾被用于取代传统的咪唑卡宾。这些化合物可用于OLED中，以提供具有改进性能的设备，例如稳定性和颜色调节。此外，还提供了一种新的合成杂环卡宾金属配合物的方法。
• METHOD OF MAKING ORGANIC ELECTROLUMINESCENT MATERIALS
  申请人：Universal Display Corporation

  公开号：US20150188062A1

  公开（公告）日：2015-07-02

  A method of forming compounds that comprise a heterocyclic carbene ligand is provided. In particular, an oxazole or a thioazole carbene are used in place of the traditional imidazole carbene. These compounds may be used in OLEDs to provide devices having improved properties, such as stability and color-tuning.

  提供了一种形成包含杂环卡宾配体的化合物的方法。特别地，使用噁唑或硫噁唑卡宾代替传统的咪唑卡宾。这些化合物可用于OLED中，以提供具有改善性能（如稳定性和色调）的设备。
• ANTI-INFLAMMATORY COMPOUND HAVING INHIBITORY ACTIVITY AGAINST MULTIPLE TYROSINE KINASES, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
  申请人：Korea Institute of Science and Technology

  公开号：EP2578590A2

  公开（公告）日：2013-04-10

  The present invention is for the anti-inflammatory compounds that have an inhibitory activity against protein tyrosine kinases and their pharmaceutical composition(s) containing the compound as the active ingredient. Since the compounds of the present invention can inhibit multiple protein kinases associated with inflammatory diseases and immune disorders, they are useful for their prevention or treatment.

  本发明涉及对蛋白酪氨酸激酶具有抑制活性的抗炎化合物及其含有该化合物作为活性成分的药物组合物。由于本发明的化合物可抑制与炎症性疾病和免疫紊乱有关的多种蛋白激酶，因此可用于预防或治疗这些疾病。
• Organic electroluminescent heterocyclic carbene metal complexes and devices containing the same
  申请人：Universal Display Corporation

  公开号：US10388890B2

  公开（公告）日：2019-08-20

  A method of forming compounds that comprise a heterocyclic carbene ligand is provided. In particular, an oxazole or a thioazole carbene are used in place of the traditional imidazole carbene. These compounds may be used in OLEDs to provide devices having improved properties, such as stability and color-tuning.

  提供了一种形成包含杂环碳烯配体的化合物的方法。特别是使用噁唑或硫唑碳烯取代传统的咪唑碳烯。这些化合物可用于有机发光二极管，以提供具有改进特性（如稳定性和色彩调节）的设备。