1-(benzyloxymethyl)-3-(4-fluorobenzyl)-6-(1-methylhydrazinyl)pyrimidine-2,4(1H,3H)-dione | 1207378-40-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1-(benzyloxymethyl)-3-(4-fluorobenzyl)-6-(1-methylhydrazinyl)pyrimidine-2,4(1H,3H)-dione
• 英文别名: 6-[Amino(methyl)amino]-3-[(4-fluorophenyl)methyl]-1-(phenylmethoxymethyl)pyrimidine-2,4-dione
• CAS: 1207378-40-2
• 化学式: C₂₀H₂₁FN₄O₃
• 分子量: 384.41
• InChiKey: RSXBJDUNDODPQN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  79.1
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Pyrimidotriazinediones and Pyrimidopyrimidinediones and Methods of Using the Same
  申请人：Showalter H.D. H.

  公开号：US20110166144A1

  公开（公告）日：2011-07-07

  The present disclosure is directed to pyrimidotriazinediones and pyrimidopyrimidinediones having a formula (I), (II), or (III), or a mixture or pharmaceutically acceptable salt or hydrate thereof, and to methods of treating cancer comprising administering the same.
• [EN] PYRIMIDOTRIAZINEDIONES AND PYRIMIDOPYRIMIDINEDIONES AND METHODS OF USING THE SAME<br/>[FR] PYRIMIDOTRIAZINEDIONES ET PYRIMIDOPYRIMIDINEDIONES ET PROCÉDÉS D'UTILISATION
  申请人：UNIV MICHIGAN

  公开号：WO2010014798A2

  公开（公告）日：2010-02-04

  The present disclosure is directed to pyrimidotriazinediones and pyrimidopyrimidinediones having a formula (I), (II), or (III), or a mixture or pharmaceutically acceptable salt or hydrate thereof, and to methods of treating cancer comprising administering the same.