(2-chloro-phenethyl)-diphenyl-silane | 95128-48-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: (2-chloro-phenethyl)-diphenyl-silane
• 英文别名: (2-chlorophenethyl)diphenylsilane；<2-(o-Chlor-phenyl)-aethyl>-diphenylsilan
• CAS: 95128-48-6
• 化学式: C₂₀H₁₉ClSi
• 分子量: 322.909
• InChiKey: PYAZYFXKLNMOHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.92
• 重原子数：
  22.0
• 可旋转键数：
  5.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  (2-chloro-phenethyl)-diphenyl-silane 在 sodium 作用下， 以 甲苯 为溶剂， 生成 1,1-diphenyl-2,3-dihydro-1H-benzo[b]silole
  参考文献：
  名称：

  Synthesis of 2:3-Benzo-1-silacycloalkenes. I

  摘要：

  DOI：

  10.1021/jo01034a013
• 作为产物：
  描述：

  邻氯苯乙酸 在 lithium aluminium tetrahydride 、 三溴化磷 作用下， 生成 (2-chloro-phenethyl)-diphenyl-silane
  参考文献：
  名称：

  Synthesis of 2:3-Benzo-1-silacycloalkenes. I

  摘要：

  DOI：

  10.1021/jo01034a013

文献信息

• Selectivity Reverse of Hydrosilylation of Aryl Alkenes Realized by Pyridine N-Oxide with [PSiP] Pincer Cobalt(III) Hydride as Catalyst
  作者：Yanhong Dong、Shangqing Xie、Peng Zhang、Qingqing Fan、Xinyu Du、Hongjian Sun、Xiaoyan Li、Olaf Fuhr、Dieter Fenske

  DOI：10.1021/acs.inorgchem.0c03483

  日期：2021.4.5

  was indirectly verified by the structures of 10–12. To our delight, the addition of pyridine N-oxide reversed the selectivity of the reaction, from anti-Markovnikov to Markovnikov addition. At the same time, the reaction temperature was reduced from 70 to 30 °C on the premise of high yield and excellent selectivity. However, this catalytic system is only applicable to aromatic alkenes. On the basis

  六甲硅烷基钴（III）氢化物1 - 6与[PSIP]钳配体具有在所述P个不同的取代基和Si原子（[（2-PH 2 PC 6 H ^ 4）2 MeSiCo（H）（Cl）的（PME 3）] （1），[（2-Ph 2 PC 6 H 4）2 HSiCo（H）（Cl）（PMe 3）]（2），[（2-Ph 2 PC 6 H 4）2 PhSiCo（H）（Cl ）（PMe 3）]（3），[（2- i Pr 2 PC 6 H4）2 HSiCo（H）（Cl）的（PME 3）]（4），[（2-我镨2 PC 6 H ^ 4）2 MeSiCo（H）（Cl）的（PME 3）]（5），和[ （2- i Pr 2 PC 6 H 4）2 PhSiCo（H）（Cl）（PMe 3）]（6）是通过配体（L1 - L6）与CoCl（PMe 3）3经由Si反应合成的-H键裂解。化合物1 - 6具有对烯烃氢化硅烷化的催化活性，其中配合
• Synthesis of silyl cobalt hydrides and their catalytic activity on hydrosilylation of alkenes
  作者：Haiquan Yang、Guoliang Chang、Xiaoyan Li、Hongjian Sun、Olaf Fuhr、Dieter Fenske

  DOI：10.1002/aoc.6774

  日期：2022.8

  Two silyl [P,Si]-chelate cobalt hydrides, [(o-Si(Ph)2-(PiPr2)C6H4)Co(H)(PMe3)2] (1) and [(o-Si(Ph)2-(PPh2)C6H4)Co(H)(PMe3)2] (2), were prepared through the chelate-assisted Si–H activation of bidentate preligand, o-HSi(Ph)2-(PiPr2)C6H4 (L1) and o-HSi(Ph)2-(PPh2)C6H4 (L2) by [Co(PMe3)4] or [Co(Me)(PMe3)4], respectively. Both cobalt(II) hydrides 1 and 2 can efficiently catalyze hydrosilylation of olefins

  两个甲硅烷基 [P,Si]-螯合钴氢化物，[( o- Si(Ph) 2 -(P i Pr 2 )C 6 H 4 )Co(H)(PMe 3 ) 2 ] ( 1 ) 和 [( o -Si(Ph) 2 -(PPh 2 )C 6 H 4 )Co(H)(PMe 3 ) 2 ] ( 2 ), 通过螯合辅助的 Si-H 活化双齿预配体o -HSi(Ph ) 2 -(P i Pr 2 )C 6 H 4 (L1 )和o -HSi(Ph) 2 -(PPh 2 )C 6 H 4 ( L2 )分别由[Co(PMe 3 ) 4 ]或[Co(Me)(PMe 3 ) 4 ]得到。氢化钴(II) 1和氢化物2均能有效催化烯烃的氢化硅烷化，配合物1的催化效果优于配合物2。Markovnikov 产物由芳基烯烃形成，而反-Markovnikov 产物由脂肪族烯烃产生。在机理研究中，甲硅烷基钴（II）中间体，[（o -Si(Ph)
• Control over Selectivity in Alkene Hydrosilylation Catalyzed by Cobalt(III) Hydride Complexes
  作者：Haiquan Yang、Alexander Hinz、Qingqing Fan、Shangqing Xie、Xinghao Qi、Wei Huang、Qingshuang Li、Hongjian Sun、Xiaoyan Li

  DOI：10.1021/acs.inorgchem.2c02094

  日期：2022.12.12

  ligand scaffolds, the three cobalt(III) hydrides show remarkably different performance as catalysts in alkene hydrosilylation. Among the PCP pincer complexes, L11 has higher catalytic activity than complex L21, and both catalysts afford anti-Markovnikov selectivity for both aliphatic and aromatic alkenes. In contrast, the catalytic activity for alkene hydrosilylation of silylene complex L31 is comparable

  两种新的双膦 [PCP] 钳形钴 (III) 氢化物，[(L 1 )Co(PMe 3 )(H)(Cl)] ( L1 1 , L 1 = 2,6-((Ph 2 P)(Et) N) 2 C 6 H 3 ) 和 [(L 2 )Co(PMe 3 )(H)(Cl)] ( L2 1 , L 2 = 2,6-(( i Pr 2 P)(Et)N) 2 C 6 H 3 ), 以及一种新的双亚甲硅基 [SiCSi] 钳形钴 (III) 氢化物, [(L 3 )Co(PMe 3 )(H)(Cl)] ( L3 1, L 3 = 1,3-((PhC( t BuN) 2 Si)(Et)N) 2 C 6 H 3 ), 通过相应的质子[PCP]或[SiCSi]钳形配体L 1 H的反应合成, L 2 H,和L 3 H与 CoCl(PMe 3 ) 3。尽管配体支架有相似之处，但三种钴 (III) 氢化物作为烯烃氢化硅烷化催化剂表现出截然不同的性能。在
• Catalytic Properties of [PSiP] Pincer Cobalt(II) Chlorides Supported by Trimethylphosphine for Alkene Hydrosilylation Reactions
  作者：Min Zhang、Yanhong Dong、Qingshuang Li、Hongjian Sun、Xiaoyan Li

  DOI：10.1021/acs.inorgchem.4c00521

  日期：2024.5.13

  catalyst, the catalytic reaction was completed within 1 h at 50 °C, predominantly affording Markovnikov products for aryl alkenes and anti-Markovnikov products for aliphatic alkene substrates. During the investigation of the catalytic mechanism, the Co(II) hydrides [(2-Ph2PC6H4)2MeSiCo(H)(PMe3)] (8) and [(2-iPr2PC6H4)2MeSiCo(H)(PMe3)] (9) were obtained from the stoichiometric reactions of complex 1 and 5

  本文制备了六基[PSiP]钳形钴(II)氯化物1–6 [(2-Ph 2 PC 6 H 4 ) 2 MeSiCo(Cl)(PMe 3 )] ( 1 ), [(2-Ph 2 PC 6 H 4 ) 2 HSiCo(Cl)(PMe 3 )] ( 2 ), [(2-Ph 2 PC 6 H 4 ) 2 PhSiCo(Cl)(PMe 3 )] ( 3 ), [(2- i Pr 2 ) PC 6 H 4 ) 2 HSiCo(Cl)(PMe 3 )] ( 4 )，[(2- i Pr 2 PC 6 H 4 ) 2 MeSiCo(Cl)(PMe 3 )] ( 5 )，和 [(2- i Pr 2 PC 6 H 4 ) 2 PhSiCo(Cl)(PMe 3 )] ( 6 )) 由相应的[PSiP]钳形预配体( L1–L6 )、CoCl 2和PMe 3通过Si-H键活化制备。研究了配合物1-6对烯烃氢化硅烷化的催化活
• General and Practical One-Pot Synthesis of Dihydrobenzosiloles from Styrenes
  作者：Alexey Kuznetsov、Vladimir Gevorgyan

  DOI：10.1021/ol203428c

  日期：2012.2.3

  A one-pot synthesis of dihydrobenzosiloles from styrenes has been developed. The reaction involves the nickel-catalyzed hydrosilylation of styrene with diphenylsilane, followed by the iridium-catalyzed dehydrogenative cyclization. This method is efficient for both electron-rich and -deficient styrenes and exhibits good functional group tolerance, as well as excellent regioselectivity. The forming dihydrobenzosiloles can be efficiently converted into valuable benzosiloles or 2-hydroxyphenethyl alcohols.