2-imino-3-(naphthalen-2-yl)thiazolidin-4-one | 406175-51-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-imino-3-(naphthalen-2-yl)thiazolidin-4-one
• 英文别名: 2-imino-3-(naphthalene-2-yl)-thiazolidin-4-one；2-imino-3-[2]naphthyl-thiazolidin-4-one；2-Imino-3-[2]naphthyl-thiazolidin-4-on；2-Imino-3-naphthalen-2-yl-1,3-thiazolidin-4-one
• CAS: 406175-51-7
• 化学式: C₁₃H₁₀N₂OS
• 分子量: 242.301
• InChiKey: BAWSEKDYKOHWFT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  69.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-imino-3-(naphthalen-2-yl)thiazolidin-4-one 、 间硝基苯甲醛 在 sodium acetate 、 溶剂黄146 作用下， 反应 5.0h， 以90.37%的产率得到2-imino-3-naphthalen-2-yl-5-[(3-nitrophenyl)methylidene]-1,3-thiazolidin-4-one
  参考文献：
  名称：

  Synthesis of Novel 2-Iminothiazolidin-4-ones

  摘要：

  Thiazolidin-4-ones are known to exhibit diverse biological activities such as antimicrobial, anticancer, antidiarrheal, anticonvulsant, antidiabetic, antihistaminic, and antifungal activities. In the present investigation, a series of 2-haloacetamides was prepared by reacting chloroacetyl chloride with amines in dry benzene under reflux conditions. The formed 2-haloacetamides reacted with potassium thiocyanate in refluxing dry acetone to afford new 2-iminothiazolidin-4-ones. The 5-arylidene-2-imino-3 (napthalen-2yl)-thiazolidin-4-ones were prepared by condensing 2-iminothiazolidin-4-ones with substituted benzaldehydes. All the products were characterized by infrared, mass, and H-1 and C-13 NMR techniques.

  DOI：

  10.1080/00397911.2011.582217
• 作为产物：
  描述：

  2-萘胺 以 丙酮 、 苯 为溶剂， 反应 3.0h， 生成 2-imino-3-(naphthalen-2-yl)thiazolidin-4-one
  参考文献：
  名称：

  Synthesis of Novel 2-Iminothiazolidin-4-ones

  摘要：

  Thiazolidin-4-ones are known to exhibit diverse biological activities such as antimicrobial, anticancer, antidiarrheal, anticonvulsant, antidiabetic, antihistaminic, and antifungal activities. In the present investigation, a series of 2-haloacetamides was prepared by reacting chloroacetyl chloride with amines in dry benzene under reflux conditions. The formed 2-haloacetamides reacted with potassium thiocyanate in refluxing dry acetone to afford new 2-iminothiazolidin-4-ones. The 5-arylidene-2-imino-3 (napthalen-2yl)-thiazolidin-4-ones were prepared by condensing 2-iminothiazolidin-4-ones with substituted benzaldehydes. All the products were characterized by infrared, mass, and H-1 and C-13 NMR techniques.

  DOI：

  10.1080/00397911.2011.582217

文献信息

• [EN] MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO<br/>[FR] MOLÉCULES PRÉSENTANT CERTAINES UTILITÉS PESTICIDES, ET INTERMÉDIAIRES, COMPOSITIONS ET PROCÉDÉS ASSOCIÉS
  申请人：CORTEVA AGRISCIENCE LLC

  公开号：WO2022132609A1

  公开（公告）日：2022-06-23

  This disclosure relates to compounds having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such compounds and intermediates used in such processes, compositions containing such compounds, and processes of using such compounds against such pests. These compounds/molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses compounds having the following formula (One).

  本公开涉及具有杀虫效用的化合物，可用于杀灭线虫门、节肢动物门和/或软体动物门的害虫，制备此类化合物的过程以及用于此类过程中的中间体，含有此类化合物的组合物以及使用此类化合物对此类害虫进行杀灭的过程。这些化合物/分子可以用作线虫杀剂、螨虫杀剂、杀虫剂、杀螨剂和/或杀软体动物剂。本文披露具有以下式子（一）的化合物。
• Johnson, Journal of the American Chemical Society, 1903, vol. 25, p. 485
  作者：Johnson

  DOI：——

  日期：——