[(E)-1-isocyanatoprop-1-en-2-yl]benzene | 83637-01-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [(E)-1-isocyanatoprop-1-en-2-yl]benzene
• CAS: 83637-01-8
• 化学式: C₁₀H₉NO
• 分子量: 159.188
• InChiKey: KSBBFJIXXZOSBB-VQHVLOKHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  29.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  6-aminopenicillanic acid trimethylsilyl ester 、 [(E)-1-isocyanatoprop-1-en-2-yl]benzene 在 sodium 2-ethylhexanoic acid 作用下， 生成 Sodium; (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[3-((E)-2-phenyl-propenyl)-ureido]-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate
  参考文献：
  名称：

  Synthesis and evaluation of ureido and vinylureidopenicillins as inhibitors of intraruminal lactic acid production

  摘要：

  A series of 14 vinylureidopenicillins and a series of 9 ureidopenicillins were prepared by reaction of 6-aminopenicillanic acid with vinyl isocyanates and isocyanates. These compounds were evaluated for their potential to protect ruminants against lactic acidosis. The compounds were tested for inhibition of in vitro ruminal lactic and propionic acid production, and six compounds inhibited lactic acid production to less than 10% of control at doses of 0.31 microgram/mL or lower, whereas they did not inhibit propionic acid production at doses greater than 10 micrograms/mL. The most active compounds also were screened for general antibacterial activity and were found to be weakly active against Gram-positive bacteria. The structure--activity relationships are discussed for both series. Triethylammonium 6-[3[2-(4-tert-butylphenyl)vinyl]ureido]penicillanate (4) was chosen for evaluation as an inhibitor of intraruminal lactic acidosis in vivo.

  DOI：

  10.1021/jm00142a024
• 作为产物：
  描述：

  (E)-3-Phenyl-but-2-enoyl azide 以 甲苯 为溶剂， 反应 1.0h， 生成 [(E)-1-isocyanatoprop-1-en-2-yl]benzene
  参考文献：
  名称：

  Synthesis and evaluation of ureido and vinylureidopenicillins as inhibitors of intraruminal lactic acid production

  摘要：

  A series of 14 vinylureidopenicillins and a series of 9 ureidopenicillins were prepared by reaction of 6-aminopenicillanic acid with vinyl isocyanates and isocyanates. These compounds were evaluated for their potential to protect ruminants against lactic acidosis. The compounds were tested for inhibition of in vitro ruminal lactic and propionic acid production, and six compounds inhibited lactic acid production to less than 10% of control at doses of 0.31 microgram/mL or lower, whereas they did not inhibit propionic acid production at doses greater than 10 micrograms/mL. The most active compounds also were screened for general antibacterial activity and were found to be weakly active against Gram-positive bacteria. The structure--activity relationships are discussed for both series. Triethylammonium 6-[3[2-(4-tert-butylphenyl)vinyl]ureido]penicillanate (4) was chosen for evaluation as an inhibitor of intraruminal lactic acidosis in vivo.

  DOI：

  10.1021/jm00142a024

文献信息

• Polymer-gebundene-Farbstoffe, Verfahren zu deren Herstellung und Verwendung
  申请人：BAYER AG

  公开号：EP0361229A2

  公开（公告）日：1990-04-04

  Die vorliegende Erfindung betrifft Polymer-gebundene-­Farbstoffe, Verfahren zu deren Herstellung und deren Verwendung wie zum Beispiel als Markierungssubstanzen in Analysenverfahren. Die Polymer-gebundenen Farbstoffe, auch Polymere Farbstoffe genannt, enthalten verknüpfbare funktionelle Gruppen und sind unter üblichen Analysenbe­dingungen wasserlöslich. Verantwortlich für diese Was­serlöslichkeit ist normalerweise der Polymeranteil. Die Farbstoffe an sich sind oft wasserunlöslich.

  本发明涉及聚合物结合染料、其制备方法及其用途，例如用作分析方法中的标记物质。聚合物结合染料又称聚合物染料，含有可连接的官能团，在正常分析条件下可溶于水。这种水溶性通常是由聚合物成分造成的。染料本身通常不溶于水。
• Silicone containing acrylic star polymers
  申请人：E.I. du Pont de Nemours and Company (a Delaware corporation)

  公开号：EP0452097A2

  公开（公告）日：1991-10-16

  Acrylic star polymers containing polysiloxanylalkyl ester groups in their arms and terminal organo groups containing a polymerizable carbon-carbon double bond are useful for improving polymer compositions for contact lenses.

  丙烯酸星型聚合物的臂部含有聚硅氧烷烷基酯基团，末端有机基团含有可聚合的碳碳双键，可用于改进隐形眼镜的聚合物组合物。
• Silicone-containing block copolymers and macromonomers
  申请人：E.I. du Pont de Nemours and Company (a Delaware corporation)

  公开号：EP0452098A2

  公开（公告）日：1991-10-16

  Copolymeric macromonomers containing alkyl acrylate and methacrylate units and units of polysiloxanylalkyl esters of acrylic and/or methacrylic acids and a terminal carbon-carbon double bond organo group are useful for copolymerizing with other acrylate or methacrylate esters to make improved polymer compositions such as for contact lenses.

  含有丙烯酸烷基酯和甲基丙烯酸酯单元以及丙烯酸和/或甲基丙烯酸的聚硅氧烷烷基酯单元和末端碳碳双键有机基团的共聚大单体，可用于与其他丙烯酸酯或甲基丙烯酸酯共聚，以制成改进的聚合物组合物，如隐形眼镜。
• Nail polish compositions
  申请人：L'OREAL

  公开号：US10058502B2

  公开（公告）日：2018-08-28

  Compositions including polycarbodiimide together with latex compounds to enhance the quality of the keratinous substrates. The present invention relates to a cosmetic treatment and process for treating keratinous materials, in particular for nail polishes and other treatments, where, according to the process, the polycarbodiimide and latex actives may be applied in a nail treatment that is a single step or at least two sequential steps. The ratio of the latex compound to the polycarbodiimide compound is in the range from about 50:50 to about 95:5, and the composition comprises 10 to 100% of a combined amount of the polycarbodiimide compound and the latex compound, by weight, of the entire composition. It is in particular a nail treatment composition and process for providing one or more of improved adhesion, water resistance, and shine through crosslinking between the actives, thereby imparting long wear, good shine, nail protection, and easy removal.

  包括聚卡波二亚胺和乳胶化合物的组合物，可提高角质基材的质量。本发明涉及一种用于处理角质材料，特别是用于指甲油和其他处理的化妆品处理方法和工艺，根据该工艺，聚卡波二亚胺和乳胶活性物质可在指甲处理过程中使用，该处理方法是一个步骤或至少两个连续步骤。乳胶化合物与聚卡波二亚胺化合物的比例范围为约 50:50 至约 95:5，按重量计，组合物中聚卡波二亚胺化合物和乳胶化合物的总量占整个组合物的 10%至 100%。本发明尤其是一种指甲处理组合物和工艺，可通过活性物之间的交联提供一种或多种改进的粘附性、防水性和光泽，从而赋予指甲长久的耐磨性、良好的光泽、指甲保护和易去除性。
• Inkjet printing on dyed synthetic fabrics
  申请人：Kornit Digital Ltd.

  公开号：US11530330B2

  公开（公告）日：2022-12-20

  An inkset and a process for direct inkjet printing color images on dyed synthetic fabrics is provided herewith, based on forming an image on the fabric in the form of a well-adhered crosslinked film, using an acid-immobilized ink composition, while avoiding dye migration from the fabric to the image in the process of curing the film, using a low-temperature curing crosslinking agent and curing the image at a temperature lower than 120±5° C.

  本发明提供了一种用于在染色合成纤维织物上直接喷墨打印彩色图像的墨组和工艺，其基础是使用酸固定墨水组合物在织物上形成粘附良好的交联薄膜形式的图像，同时在固化薄膜的过程中避免染料从织物迁移到图像上，使用低温固化交联剂并在低于 120±5°C 的温度下固化图像。