2,4,6-tri(hydroxylmethyl)pyridine | 87512-10-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,4,6-tri(hydroxylmethyl)pyridine
• 英文别名: [2,6-Bis(hydroxymethyl)pyridin-4-yl]methanol
• CAS: 87512-10-5
• 化学式: C₈H₁₁NO₃
• 分子量: 169.18
• InChiKey: CLQWIZGOHRJBNS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  73.6
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,4,6-tri(hydroxylmethyl)pyridine 在 戴斯-马丁氧化剂 作用下， 以 二氯甲烷 为溶剂， 生成 2,4,6-Triformyl-pyridin
  参考文献：
  名称：

  ANTI-INFLAMMATORY COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF TREATING HEMOCHROMATOSIS, AND OTHER DISORDERS

  摘要：

  Pharmaceutical compounds have anti-inflammatory activity. A pharmaceutical composition may include a therapeutically effective amount of the compound(s) and a pharmaceutically acceptable vehicle. A method of treating hemochromatosis, hyperammonemia, or a disorder associated with chronic inflammation or a cancer, involves administering the pharmaceutical composition to an individual in need thereof. In another aspect, a method of inhibiting formation of metal oxides or reducing metal reactivity comprises contacting a metal with an effective amount of the compound(s).

  公开号：

  WO2024050374A2
• 作为产物：
  描述：

  在 盐酸 、 甲醇 、 sodium tetrahydroborate 、 水 作用下， 反应 16.0h， 生成 2,4,6-tri(hydroxylmethyl)pyridine
  参考文献：
  名称：

  ANTI-INFLAMMATORY COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF TREATING HEMOCHROMATOSIS, AND OTHER DISORDERS

  摘要：

  Pharmaceutical compounds have anti-inflammatory activity. A pharmaceutical composition may include a therapeutically effective amount of the compound(s) and a pharmaceutically acceptable vehicle. A method of treating hemochromatosis, hyperammonemia, or a disorder associated with chronic inflammation or a cancer, involves administering the pharmaceutical composition to an individual in need thereof. In another aspect, a method of inhibiting formation of metal oxides or reducing metal reactivity comprises contacting a metal with an effective amount of the compound(s).

  公开号：

  WO2024050374A2

文献信息

• Synthesis and Luminescence Properties of Lanthanide Complexes of a Novel Polyaminopolycarboxylate Ligand
  作者：Chang-Quan Tang、Rui-Ren Tang、Chun-Hua Tang、Zhi-Wen Zeng

  DOI：10.5012/bkcs.2010.31.5.1283

  日期：2010.5.20

  sensitized efficiently by the liga nd, especially the Tb(III) complex displayed a very strong luminescence intensity (> 10000) and only displayed characteristic metal-centered luminescence. Also, the correlative comparison between the structure of ligand and luminescence properties showed how the number of the coordination atoms of ligand can be a prominent factor in the effectiveness of ligand-to-metal

  离子可以被配体有效地敏化，特别是 Tb(III) 配合物显示出非常强的发光强度 (> 10000) 并且仅显示出特征性的金属中心发光。此外，配体结构与发光特性之间的相关比较表明，配体的配位原子数如何成为影响配体-金属能量转移有效性的重要因素。
• Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US10921650B2

  公开（公告）日：2021-02-16

  The present invention relates to a liquid crystal aligning agent which contains a polymer that has a site having an isocyanate group and/or a blocked isocyanate group, a site having a photoreactive group having photoalignment, and a site having at least one functional group selected from an amino group and a hydroxyl group in each molecule. The present invention provides a liquid crystal display element which enables baking at low temperatures during the formation of a liquid crystal alignment film by a photoalignment method, the liquid crystal alignment film being able to be imparted with alignment regulating property and pretilt angle developing property.

  本发明涉及一种液晶配向剂，该液晶配向剂含有一种聚合物，该聚合物在每个分子中具有具有异氰酸酯基团和/或封端异氰酸酯基团的位点、具有光配位的光活性基团的位点以及具有至少一个选自氨基和羟基的官能团的位点。本发明提供了一种液晶显示元件，在通过光配位法形成液晶配位膜的过程中，可在低温下进行烘烤，该液晶配位膜能够被赋予配位调节特性和前倾角度显影特性。
• Liquid crystal aligning agent containing crosslinking agent and polymer that has site having isocyanate group and/or blocked isocyanate group and site having photoreactivity, liquid crystal alignment film, and liquid crystal display element
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US11028323B2

  公开（公告）日：2021-06-08

  Provided is a liquid crystal display element that can be baked at a low temperature when forming a liquid crystal alignment film capable of imparting an alignment regulating property and a pretilt angle developing property via a photoalignment method. Further provided is a liquid crystal display element in which the liquid crystal pretilt angles are highly stable, and display burn-in hardly occurs even due to long usage. Further provided are a vertical liquid crystal alignment film to be used in the liquid crystal display element, and a liquid crystal aligning agent with which it is possible to provide the vertical liquid crystal alignment film. A liquid crystal aligning agent of the present invention contains: component (A), which is a polymer including (A-1) a site having an isocyanate group and/or a blocked isocyanate group and (A-2) a site having photoreactivity; component (B), which is a compound having, in a molecule, at least two functional groups of at least one type selected from the group consisting of an amino group and a hydroxyl group; and an organic solvent.

  本发明提供了一种液晶显示元件，该元件在形成液晶对准膜时可在低温下烘烤，通过光对准方法赋予对准调节特性和预倾斜角显影特性。本发明还提供了一种液晶显示元件，其液晶前倾角高度稳定，即使长时间使用也几乎不会出现显示烧损。还提供了一种用于液晶显示元件的垂直液晶对准膜，以及一种可提供垂直液晶对准膜的液晶对准剂。本发明的液晶对准剂包含：成分（A），即聚合物，包括（A-1）具有异氰酸酯基团和/或封端异氰酸酯基团的位点和（A-2）具有光活性的位点；成分（B），即化合物，在分子中具有至少两种官能团，其中至少一种官能团选自氨基和羟基组成的组；以及有机溶剂。
• Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer
  申请人：NAKAHARA Shinya

  公开号：US20080227937A1

  公开（公告）日：2008-09-18

  A process for producing an olefin copolymerization catalyst, comprising the step of contacting, with one another, (A) a solid catalyst component containing a titanium atom, a magnesium atom and a halogen atom, (B) an organoaluminum compound and/or organoaluminumoxy compound, and (C) a nitrogen-containing aromatic heterocyclic compound, whose one or more carbon atoms adjacent to its nitrogen atom are linked to an electron-donating group, or a group containing an electron-donating group; and a process for producing an olefin copolymer using the an olefin copolymerization catalyst.
• LIQUID CRYSTAL ALIGNING AGENT CONTAINING CROSSLINKING AGENT AND POLYMER THAT HAS SITE HAVING ISOCYANATE GROUP AND/OR BLOCKED ISOCYANATE GROUP AND SITE HAVING PHOTOREACTIVITY, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US20190023987A1

  公开（公告）日：2019-01-24

  Provided is a liquid crystal display element that can be baked at a low temperature when forming a liquid crystal alignment film capable of imparting an alignment regulating property and a pretilt angle developing property via a photoalignment method. Further provided is a liquid crystal display element in which the liquid crystal pretilt angles are highly stable, and display burn-in hardly occurs even due to long usage. Further provided are a vertical liquid crystal alignment film to be used in the liquid crystal display element, and a liquid crystal aligning agent with which it is possible to provide the vertical liquid crystal alignment film. A liquid crystal aligning agent of the present invention contains: component (A), which is a polymer including (A-1) a site having an isocyanate group and/or a blocked isocyanate group and (A-2) a site having photoreactivity; component (B), which is a compound having, in a molecule, at least two functional groups of at least one type selected from the group consisting of an amino group and a hydroxyl group; and an organic solvent.