2-(4-Methyl-phenylmercapto)-1-dimethylamino-aethan | 153914-75-1

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2-(4-Methyl-phenylmercapto)-1-dimethylamino-aethan
• 英文别名: N,N-dimethyl-2-(4-methylphenyl)sulfanylethanamine
• CAS: 153914-75-1
• 化学式: C₁₁H₁₇NS
• 分子量: 195.329
• InChiKey: MLKIXQQTOLMTQL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  28.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  tetrameric trimethylplatinum(IV) chloride 、 2-(4-Methyl-phenylmercapto)-1-dimethylamino-aethan 以 苯 为溶剂， 以35%的产率得到
  参考文献：
  名称：

  Synthesis and characterization of trimethylplatinum(IV) complexes with (2-dimethylaminoethyl)organochalcogenides (Me2NCH2CH2ER; E = S, Se, Te). X-ray crystal structure of [PtMe3Br(Me2NCH2CH2SC6H4Me-4)]

  摘要：

  Trimethylplatinum(IV) complexes of the type [PtMe3X(Me2NCH2CH2ER)] (X = Cl, Br, I; ER = SBu(t), SC6H4Me-4, SPh, SePh, TePh) have been prepared and characterized by elemental analysis and NMR (H-1 and C-13) spectral data. The structure of [PtMe3Br(Me2NCH2CH2SC6H4Me-4)] has been determined by single-crystal X-ray diffraction. The central platinum atom is coordinated by three fac-methyl groups and nitrogen, sulphur and bromine atoms. The five-membered chelate ring PtNCCS is non-planar.

  DOI：

  10.1016/s0277-5387(00)83057-0
• 作为产物：
  描述：

  二甲氨基氯乙烷盐酸 、 potassium p-tolylthiolate 以 乙醇 为溶剂， 生成 2-(4-Methyl-phenylmercapto)-1-dimethylamino-aethan
  参考文献：
  名称：

  Pagani; Borgna; Baruffini, Farmaco, Edizione Scientifica, 1967, vol. 22, # 7, p. 519 - 527

  摘要：

  DOI：

文献信息

• INHIBITION OF ACTIVATED CDC42-ASSOCIATED KINASE 1
  申请人：Peterson Jeffrey R.

  公开号：US20120245173A1

  公开（公告）日：2012-09-27

  Compounds, compositions, and methods for specific inhibition of activated cdc42-associated kinase 1 (Ack1) are provided.
• Pagani; Borgna; Baruffini, Farmaco, Edizione Scientifica, 1967, vol. 22, # 7, p. 519 - 527
  作者：Pagani、Borgna、Baruffini

  DOI：——

  日期：——
• Synthesis and characterization of trimethylplatinum(IV) complexes with (2-dimethylaminoethyl)organochalcogenides (Me2NCH2CH2ER; E = S, Se, Te). X-ray crystal structure of [PtMe3Br(Me2NCH2CH2SC6H4Me-4)]
  作者：Vimal K. Jain、Satyajeet Chaudhury、Rakesh Bohra

  DOI：10.1016/s0277-5387(00)83057-0

  日期：1993.10

  Trimethylplatinum(IV) complexes of the type [PtMe3X(Me2NCH2CH2ER)] (X = Cl, Br, I; ER = SBu(t), SC6H4Me-4, SPh, SePh, TePh) have been prepared and characterized by elemental analysis and NMR (H-1 and C-13) spectral data. The structure of [PtMe3Br(Me2NCH2CH2SC6H4Me-4)] has been determined by single-crystal X-ray diffraction. The central platinum atom is coordinated by three fac-methyl groups and nitrogen, sulphur and bromine atoms. The five-membered chelate ring PtNCCS is non-planar.