4-amino-1-methylpyrimidin-2-one;dichloroplatinum | 596796-12-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 4-amino-1-methylpyrimidin-2-one;dichloroplatinum
• CAS: 596796-12-2
• 化学式: C₁₅H₂₁ClN₉O₃Pt*Cl
• 分子量: 641.376
• InChiKey: RPDOYPYXWXICPO-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  4-amino-1-methylpyrimidin-2-one;dichloroplatinum 、 potassium iodide 在 HClO₄ 作用下， 以 水 为溶剂， 生成 trans-Pt(1-methylcytosine-N(3))2I2
  参考文献：
  名称：

  Diplatinum(III) Complexes with Four Bridging 1-Methylcytosinato Nucleobases Derived from a Mononuclear trans-(NH₃)₂Pt^II Complex and Cu^II

  摘要：

  A heteronuclear complex of composition trans-[(NH3)(2)Pt(N4-1-MeC--N3)(2)Cu(H2O)(2)](ClO4)2 (1a), with 1-MeC- = 1-methylcytosinate, has been prepared and characterized by X-ray crystallography. 1a (Cu,Pt) is a linkage isomer of a previously described compound with the two metals inverted (Pt,Cu). The intermetallic distances are significantly different in the two types of compounds, 2.6109(9) Angstrom in 1a, yet 2.49-2.56 Angstrom in several forms of the linkage isomer. When heated in water in the presence of air, la is converted in low yield into diplatinum(III) compounds [(H3N)Pt(1-MeC--N3,N4)(4)Pt(NH3)](2+) (2a) and [(H2O)Pt(1-MeC--N3,N4)(4)Pt(NH3)](2+) (2b), which were crystallized as ClO4- salts. In a modified procedure a third representative of this g,roup of diplatinum(III) compounds, [(O2N)Pt(1-MeC--N3,N4)(4)Pt](+) (2c) was isolated. All three compounds contain the four bridging 1-MeC ligands in a head, tail, head, tail arrangement with Pt-Pt distances (2.4516(7)-2.4976(9) Angstrom) that are the shortest ones among diplatinum(III) compounds containing nucleobases.

  DOI：

  10.1021/ic0343152