4-Methyl-5-(2-pyrazinyl)-1.2-dithiol-3-thion | 69211-52-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 4-Methyl-5-(2-pyrazinyl)-1.2-dithiol-3-thion
• 英文别名: 4-Methyl-5-pyrazin-2-yldithiolane-3-thione
• CAS: 69211-52-5
• 化学式: C₈H₈N₂S₃
• 分子量: 228.363
• InChiKey: BKYHLLIVLBEROA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  109
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Formulations of 4-methyl-5-(pyrazin-2-yl)-3H-l,2-dithiole-3-thione, taste-modified formulations, and methods of making and using same
  申请人：ST IP Holding AG

  公开号：US11185544B2

  公开（公告）日：2021-11-30

  This disclosure provides, among other things, compositions comprising quantities of oltipraz crystals, as well as method of making such compositions, and method of treating patients using such compositions. Taste-modified compositions also are provided.

  除其他外，本公开提供了包含一定量奥利司他晶体的组合物，以及制作此类组合物的方法和使用此类组合物治疗患者的方法。此外，还提供了改良口味的组合物。
• Formulations of 4-Methyl-5-(Pyrazin-2-yl)-3H-1,2-Dithiole-3-Thione, Taste-Modified Formulations, and Methods of Making and Using Same
  申请人：ST IP Holding AG

  公开号：US20190209557A1

  公开（公告）日：2019-07-11

  This disclosure provides, among other things, compositions comprising quantities of oltipraz crystals, as well as method of making such compositions, and method of treating patients using such compositions. Taste-modified compositions also are provided.