5,6-Dimethoxy-6-phenylcyclohexa-2,4-dien-1-one | 450357-38-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5,6-Dimethoxy-6-phenylcyclohexa-2,4-dien-1-one
• CAS: 450357-38-7
• 化学式: C₁₄H₁₄O₃
• 分子量: 230.263
• InChiKey: FPQPJQGHCCPFFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  乙烯氧基甲基-苯 、 5,6-Dimethoxy-6-phenylcyclohexa-2,4-dien-1-one 反应 72.0h， 以76%的产率得到
  参考文献：
  名称：

  Complete π-Facial Diastereoselectivity in Diels−Alder Reactions of Dissymmetric 2,4-Cyclohexadienones

  摘要：

  [GRAPHIC]The studies in the Diels-Alder reactions of 5-methoxy-masked o-benzoquinone (1a, R = OMe) and simple dissymmetric 2,4-cyclohexadienones 1b-e with methyl vinyl ketone, styrene, and benzyl vinyl ether are described. The dienones 1b-e reacted with dienophiles to form syn adducts (dienophile approach is syn to allylic methoxy group) exclusively.

  DOI：

  10.1021/ol020087o
• 作为产物：
  描述：

  5,6,6-trimethoxycyclohexa-2,4-dienone 在 二氯乙基铝 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 生成 5,6-Dimethoxy-6-phenylcyclohexa-2,4-dien-1-one
  参考文献：
  名称：

  Complete π-Facial Diastereoselectivity in Diels−Alder Reactions of Dissymmetric 2,4-Cyclohexadienones

  摘要：

  [GRAPHIC]The studies in the Diels-Alder reactions of 5-methoxy-masked o-benzoquinone (1a, R = OMe) and simple dissymmetric 2,4-cyclohexadienones 1b-e with methyl vinyl ketone, styrene, and benzyl vinyl ether are described. The dienones 1b-e reacted with dienophiles to form syn adducts (dienophile approach is syn to allylic methoxy group) exclusively.

  DOI：

  10.1021/ol020087o

文献信息

• Complete π-Facial Diastereoselectivity in Diels−Alder Reactions of Dissymmetric 2,4-Cyclohexadienones
  作者：Hui-Fang Hou、Rama Krishna Peddinti、Chun-Chen Liao

  DOI：10.1021/ol020087o

  日期：2002.7.1

  [GRAPHIC]The studies in the Diels-Alder reactions of 5-methoxy-masked o-benzoquinone (1a, R = OMe) and simple dissymmetric 2,4-cyclohexadienones 1b-e with methyl vinyl ketone, styrene, and benzyl vinyl ether are described. The dienones 1b-e reacted with dienophiles to form syn adducts (dienophile approach is syn to allylic methoxy group) exclusively.