2-Iodo-6-(methoxymethoxy)-3-nitrobenzaldehyde | 139277-46-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Iodo-6-(methoxymethoxy)-3-nitrobenzaldehyde
• 英文别名: 2-iodo-6-(methoxymethoxy)-3-nitrobenzaldehyde
• CAS: 139277-46-6
• 化学式: C₉H₈INO₅
• 分子量: 337.071
• InChiKey: NQWRAJMSDSGLTE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  81.4
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-Iodo-6-(methoxymethoxy)-3-nitrobenzaldehyde 在 盐酸 、 PdCl₂(PPh₃)32 作用下， 以 甲醇 、 水 、 甲苯 为溶剂， 反应 4.0h， 生成 6-(6-hydroxy-4-oxa-hex-1-ynyl)-5-nitrosalicylaldehyde
  参考文献：
  名称：

  New Crown Spirobenzopyrans as Light- and Ion-Responsive Dual-Mode Signal Transducers

  摘要：

  A new class of crown spirobenzopyrans were designed and synthesized. The crown spirobenzopyrans showed thermally irreversible photochromism only in the presence of alkali-metal cations accompanying cation-selective coloring efficiency. Thus, the new crown spirobenzopyrans could transmit information of two different simultaneous stimuli (ion and photon) to changes in their optical properties. The dual-mode signal transducer molecules developed here can be considered to perform ''AND'' gate type signal transduction based on photochromism of artificial receptors. Molecular recognition abilities and photochromic properties of the new crown spirobenzopyrans were characterized by use of NMR and FAB mass spectroscopies.

  DOI：

  10.1021/ja9707668
• 作为产物：
  描述：

  4-吲哚-3-硝基酚 在 sodium hydride 作用下， 以 四氢呋喃 、 三氟乙酸 为溶剂， 反应 6.0h， 生成 2-Iodo-6-(methoxymethoxy)-3-nitrobenzaldehyde
  参考文献：
  名称：

  New Crown Spirobenzopyrans as Light- and Ion-Responsive Dual-Mode Signal Transducers

  摘要：

  A new class of crown spirobenzopyrans were designed and synthesized. The crown spirobenzopyrans showed thermally irreversible photochromism only in the presence of alkali-metal cations accompanying cation-selective coloring efficiency. Thus, the new crown spirobenzopyrans could transmit information of two different simultaneous stimuli (ion and photon) to changes in their optical properties. The dual-mode signal transducer molecules developed here can be considered to perform ''AND'' gate type signal transduction based on photochromism of artificial receptors. Molecular recognition abilities and photochromic properties of the new crown spirobenzopyrans were characterized by use of NMR and FAB mass spectroscopies.

  DOI：

  10.1021/ja9707668

文献信息

• Transmission of recognition information to other sites in a molecule: proximity of two remote sites in the spirobenzopyran by recognition of alkali-metal cations
  作者：Masahiko Inouye、Masaru Ueno、Teijiro Kitao

  DOI：10.1021/jo00032a005

  日期：1992.3

  A new spirobenzopyran was synthesized, in which recognition of alkali-metal cations induced a structural change in the molecule accompanying coloration that resulted in a proximity of two remote sites in the molecule.
• New Crown Spirobenzopyrans as Light- and Ion-Responsive Dual-Mode Signal Transducers
  作者：Masahiko Inouye、Kaori Akamatsu、Hiroyuki Nakazumi

  DOI：10.1021/ja9707668

  日期：1997.10.1

  A new class of crown spirobenzopyrans were designed and synthesized. The crown spirobenzopyrans showed thermally irreversible photochromism only in the presence of alkali-metal cations accompanying cation-selective coloring efficiency. Thus, the new crown spirobenzopyrans could transmit information of two different simultaneous stimuli (ion and photon) to changes in their optical properties. The dual-mode signal transducer molecules developed here can be considered to perform ''AND'' gate type signal transduction based on photochromism of artificial receptors. Molecular recognition abilities and photochromic properties of the new crown spirobenzopyrans were characterized by use of NMR and FAB mass spectroscopies.