11-Methyl-5,6-dihydro-6-oxo-dibenz-5-azepin | 2183-70-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯氮卓类
• 英文名称: 11-Methyl-5,6-dihydro-6-oxo-dibenz-5-azepin
• 英文别名: 5,11-Dihydro-11-methyl-6H-dibenz[b,e]azepin-6-one；11-methyl-5,11-dihydrobenzo[c][1]benzazepin-6-one
• CAS: 2183-70-2
• 化学式: C₁₅H₁₃NO
• 分子量: 223.274
• InChiKey: MPYQKZPERZKQGJ-UHFFFAOYSA-N

物化性质

• 熔点：
  202-205 °C
• 沸点：
  281.6±20.0 °C(Predicted)
• 密度：
  1.137±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• SUBSTITUTED POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE
  申请人：Shionogi & Co., Ltd.

  公开号：EP2444400B1

  公开（公告）日：2018-03-28
• SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG
  申请人：Shionogi & Co., Ltd.

  公开号：US20150111854A1

  公开（公告）日：2015-04-23

  The present invention provides a compound having antiviral effects, particularly having growth inhibitory activity on influenza viruses, a preferred example of the compound being a substituted 3-hydroxy-4-pyridone derivative prodrug having cap-dependent endonuclease inhibitory activity.
• SUBSTITUTED POLYCYCLIC CARBAMOLYPYRIDONE DERIVATIVE
  申请人：Shionogi & Co., Ltd.

  公开号：US20160368921A1

  公开（公告）日：2016-12-22

  This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having cap-dependent endonuclease inhibitory activity.
• US8927710B2
  申请人：——

  公开号：US8927710B2

  公开（公告）日：2015-01-06
• US8987441B2
  申请人：——

  公开号：US8987441B2

  公开（公告）日：2015-03-24