6-phenyl-4-pyrimidinemethanamine | 1083396-46-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 6-phenyl-4-pyrimidinemethanamine
• 英文别名: (6-Phenylpyrimidin-4-yl)methanamine
• CAS: 1083396-46-6
• 化学式: C₁₁H₁₁N₃
• 分子量: 185.228
• InChiKey: JMZVWZAKTSCVEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  51.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS<br/>[FR] NOUVEAUX AGONISTES DE RÉCEPTEURS ADRÉNERGIQUES BÊTA 3 DÉRIVÉS DE PYRROLIDINE
  申请人：MERCK SHARP & DOHME

  公开号：WO2011025774A1

  公开（公告）日：2011-03-03

  The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.

  本发明提供了式(I)的化合物，其药物组成物以及使用该化合物在治疗或预防由β3-肾上腺素受体激活介导的疾病的方法。
• NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS
  申请人：Edmondson Scott D.

  公开号：US20120157432A1

  公开（公告）日：2012-06-21

  The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.

  本发明提供公式（I）的化合物、其制药组合物以及使用该化合物治疗或预防通过激活β3-肾上腺素受体介导的疾病的方法。
• Pyridine compounds as fungicides
  申请人：BASF SE

  公开号：US10696634B2

  公开（公告）日：2020-06-30

  The present invention relates to compounds I wherein the variables are defined as given in the description and claims. The invention further relates to uses, processes and intermediates for compounds I.

  本发明涉及化合物 I 其中各变量的定义见说明书和权利要求书。本发明还涉及化合物 I 的用途、工艺和中间体。
• PYRIDINE COMPOUNDS
  申请人：BASF SE

  公开号：US20200187500A1

  公开（公告）日：2020-06-18

  The present invention relates to compounds of formula I wherein the variables are defined as given in the description and claims. The invention further relates to uses and composition for compounds of formula I.
• NEW PYRIDINE CARBOXAMIDES
  申请人：BASF SE

  公开号：US20200354321A1

  公开（公告）日：2020-11-12

  The present invention relates to the use of compounds of formula I, wherein the variables are defined as given in the description and claims. The invention further relates to the compounds I and composition for compounds of formula I.