1,3-苯二锂 | 2592-85-0

• 分子结构分类: 有机化合物 - 苯类化合物
• 中文名称: 1,3-苯二锂
• 英文名称: 1,3-dilithiobenzene
• CAS: 2592-85-0
• 化学式: C₆H₄Li₂
• 分子量: 89.9798
• InChiKey: VOTZHAZMXFYESM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.51
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,3-苯二锂 在 platinum(IV) oxide 氢气 作用下， 生成 ethyl (2S,5R)-5-[3-[(2R,5S)-5-ethoxycarbonylpyrrolidin-2-yl]phenyl]pyrrolidine-2-carboxylate
  参考文献：
  名称：

  Novel dirhodium tetraprolinate catalysts containing bridging prolinate ligands for asymmetric carbenoid reactions

  摘要：

  The D-2-symmetric dirhodium prolinate complex 3 is an effective catalyst for asymmetric vinylcarbenoid and phenylcarbenoid cyclopropanations. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01000-x

文献信息

• Formation of 1,3,5-Trilithiobenzene and Its Conversion to the Corresponding Magnesium, Mercury, and Tin Derivatives
  作者：Nicolette Rot、Friedrich Bickelhaupt

  DOI：10.1021/om9705620

  日期：1997.11.1

  Whereas the halogen−metal exchange approach from 1,3,5-tribromobenzene (3) to 1,3,5-trilithiobenzene (1) was unsuccessful, 1 was synthesized in high yield (about 80%) by reaction of 3 with LiDBB (lithium 4,4‘-di-tert-butylbiphenyl). Compound 1 was used as the starting material for the preparation of other symmetrical trimetalated benzenes, 1,3,5-C6H3(MgBr)3 (20), 1,3,5-C6H3(SnMe3)3 (23), and 1,3,5-C6H3(HgBr)3

  从1,3,5-三溴苯（3）到1,3,5-三苯硫基苯（1）的卤素-金属交换方法不成功，但通过3与LiDBB的反应（1）可以高收率（约80％）合成1。 4,4'-二叔丁基联苯锂）。化合物1用作制备其他对称三金属苯的原料，1,3,5-C 6 H 3（MgBr）3（20），1,3,5-C 6 H 3（SnMe 3）3（23）和1,3,5-C 6 H 3（HgBr）3（26），通过与相应的金属卤化物反应。
• Building with Cubane-1,4-diyl. Synthesis of Aryl-Substituted Cubanes, <i>p</i>-[<i>n</i>]Cubyls, and Cubane-Separated Bis(arenes)¹
  作者：Philip E. Eaton、Kakumanu Pramod、Todd Emrick、Richard Gilardi

  DOI：10.1021/ja983441f

  日期：1999.5.1

  On treatment with an organolithium 1,4-diiodocubane generates cubane-1,4-diyl, a highly reactive species, shown here to be a versatile precursor to numerous aryl substituted cubanes, available now for the first time in high yield. The diyl is demonstrated to provide a good route to bicubyl and its derivatives. A kind of "living polymerization" of the diyl is developed to give the p-[n]cubyls. These oligomers are rigid rods made up of cubanes linked together at the 1 and 4 positions, each cubane adding similar to 4.15 Angstrom to the length. The properties of these rods, some more than 15 Angstrom long, are discussed, as are methods for modifying their solubility. X-ray crystallographic analyses of some of these compounds an presented, with emphasis on packing parameters.
• Catenation of Two Singlet Diradicals: Synthesis of a Stable Tetraradical (Tetraradicaloid)
  作者：Amor Rodriguez、Fook S. Tham、Wolfgang W. Schoeller、Guy Bertrand

  DOI：10.1002/anie.200460473

  日期：2004.9.20