申请人:Bhandari Kalpana
公开号:US20050215631A1
公开(公告)日:2005-09-29
The present invention provides N-aryloxypropanolyl-N′-phenethyl-urea derivatives of formula 3, method for their preparation and use thereof as potent appetite suppressants for treatment of obesity
wherein R is selected from the group consisting of H, 2, 3 or 4-trifluoromethyl, 2, 3, or 4-chloro, 2, 3, or 4-bromo, 4-acetyl, 4-propionyl, 4-acetamido, 2, 3 or 4 methoxy, 4 nitrile, 2, 3 or 4-methyl, and 4 formyl and X is S or O.
本发明提供了公式3的N-芳氧基丙酰基-N'-苯乙基脲衍生物,其制备方法以及作为治疗肥胖症的有效食欲抑制剂的用途,其中R从H,2,3或4-三氟甲基,2,3或4-氯,2,3或4-溴,4-乙酰基,4-丙酰基,4-乙酰胺基,2,3或4-甲氧基,4-腈基,2,3或4-甲基和4-甲酰基的群中选择,X为S或O。