N-(4-nitro-benzoyl)-L-serine | 92520-18-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-nitro-benzoyl)-L-serine
• 英文别名: N-(4-Nitro-benzoyl)-L-serin；p-Nitrobenzoyl-l-serin；(2S)-3-hydroxy-2-[(4-nitrobenzoyl)amino]propanoic acid
• CAS: 92520-18-8
• 化学式: C₁₀H₁₀N₂O₆
• mdl: MFCD16378804
• 分子量: 254.199
• InChiKey: KAVPRMRVGHWEKH-QMMMGPOBSA-N

物化性质

• 沸点：
  590.8±50.0 °C(Predicted)
• 密度：
  1.520±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  132
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  L-丝氨酸 、 4-nitrophenyl 4-nitrobenzoate 以 水 、 异丙醇 为溶剂， 生成 N-(4-nitro-benzoyl)-L-serine
  参考文献：
  名称：

  Effect of the Composition of the Aqueous Organic Solvent on the Kinetics of N-Acylation of α-Amino Acids with 4-Nitrophenyl 4-Nitrobenzoate

  摘要：

  Equations relating the N-acylation rate constants of glycine, L-alpha-alanine, DL-threonine, and L-proline with 4-nitrophenyl 4-nitrobenzoate in water-acetonitrile, water-2-propanol, and water-2-methyl-2-propanol solvents to the composition of the medium were obtained, and reaction rate constants in water were calculated.

  DOI：

  10.1023/b:rugc.0000025506.20666.d8

文献信息

• JPH1171224A
  申请人：——

  公开号：JPH1171224A

  公开（公告）日：1999-03-16
• Effect of the Composition of the Aqueous Organic Solvent on the Kinetics of N-Acylation of α-Amino Acids with 4-Nitrophenyl 4-Nitrobenzoate
  作者：A. Yu. Lebedukho、L. V. Kuritsyn、A. I. Sadovnikov

  DOI：10.1023/b:rugc.0000025506.20666.d8

  日期：2004.2

  Equations relating the N-acylation rate constants of glycine, L-alpha-alanine, DL-threonine, and L-proline with 4-nitrophenyl 4-nitrobenzoate in water-acetonitrile, water-2-propanol, and water-2-methyl-2-propanol solvents to the composition of the medium were obtained, and reaction rate constants in water were calculated.