carnitine acetate | 932398-33-9

• 分子结构分类: 有机化合物
• 英文名称: carnitine acetate
• 英文别名: Acetic acid;3-hydroxy-4-(trimethylazaniumyl)butanoate
• CAS: 932398-33-9
• 化学式: C₂H₃O₂*C₇H₁₆NO₃
• 分子量: 221.254
• InChiKey: LIWJYKKPRGJLOQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.72
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  97.7
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  carnitinenitrile acetate 在 modified manganese dioxide containing vanadium 水 作用下， 反应 2.0h， 以89.9%的产率得到carnitine amide acetate
  参考文献：
  名称：

  WO2007/37082

  摘要：

  公开号：

文献信息

• PROCESS FOR PRODUCING CARNITINAMIDE
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP1930314A1

  公开（公告）日：2008-06-11

  A process for producing carnitinamide which is an intermediate for production of L-carnitine is provided, which can hydrate carnitine nitrile to form carnitinamide with high selectivity, whereby highly-purified carnitinamide excellent as a substrate for stereoselective hydrolysis by optical resolution or a microorganism is produced in high yield. The process comprises hydrating carnitine nitrile to form carnitinamide using a catalyst containing a manganese oxide, and thus carnitinamide substantially free from by-produced carnitine is produced in high yield, so that carnitinamide of extremely high purity can be obtained through simple and easy crystallization operation.

  本发明提供了一种生产左旋肉碱中间体的肉毒碱酰胺的工艺，该工艺可以高选择性地将肉毒碱腈水合形成肉毒碱酰胺，从而高产率地生产出高纯度的肉毒碱酰胺，该肉毒碱酰胺是通过光学解析或微生物进行立体选择性水解的优良底物。该工艺包括使用含有氧化锰的催化剂将肉碱腈水合形成肉碱酰胺，从而高产率地生产出基本不含副产肉碱的肉碱酰胺，这样就可以通过简单易行的结晶操作获得纯度极高的肉碱酰胺。
• COMPOSITION CONTAINING ORGANIC AMMONIUM SALT
  申请人：Miyoshi Oil & Fat Co., Ltd.

  公开号：EP3925672A1

  公开（公告）日：2021-12-22

  Provided is a novel composition with excellent stability which contains an organic ammonium salt. The composition containing an organic ammonium salt of the present invention contains an organic ammonium salt having a hydrogen-bonding functional group(s) in a cation and/or an anion, and a surfactant.

  本发明提供了一种稳定性极佳的新型组合物，其中含有一种有机铵盐。 本发明中含有有机铵盐的组合物包含一种在阳离子和/或阴离子中具有氢键官能团的有机铵盐和一种表面活性剂。
• Sustained release eye drop formulations
  申请人：Ramscor, Inc.

  公开号：US10744202B2

  公开（公告）日：2020-08-18

  This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably α-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.

  本发明提供了生物相容性、可生物降解的滴眼液药物制剂，可用于治疗眼部疾病。特别是，生育酚及其低水溶性酯类，尤其是 α-生育酚乙酸酯，是生物相容性、无刺激性、可持续释放活性剂的外用眼药水制剂的理想载体。
• Formulation of flavones and isoflavones for treatment of cellulite
  申请人：——

  公开号：US20020106388A1

  公开（公告）日：2002-08-08

  Disclosed is a treatment protocol and formulation for the cosmetic condition known as cellulite. The active ingredients of the several formulation include isoflavones, like genistein, a hydroxyflavone, like quercetin, a xanthine derivative, like theophylline, a carnitine, and a plant extract like coleus forskohlii. In the emusion form, standard emulsifiers, emollients, and preservatives are utilized. In the microencapsulated form, the slurry also includes a carrier and preservative, which facilitates a slurry that is used to impregnate body garments, like pantyhose, for extended application to the user's skin.

  本发明公开了一种治疗方案和配方，用于治疗被称为橘皮组织的美容病症。几种配方的活性成分包括异黄酮（如染料木素）、羟基黄酮（如槲皮素）、黄嘌呤衍生物（如茶碱）、肉碱和植物提取物（如薏苡仁）。在乳剂形式中，使用标准乳化剂、润肤剂和防腐剂。在微胶囊形式中，浆液还包括载体和防腐剂，这有利于浆液用于浸渍身体服装（如连裤袜），以便长时间涂抹在使用者的皮肤上。
• NUTRITIONAL COMPOSITION FOR WEIGHT MANAGEMENT
  申请人：THE IAMS COMPANY

  公开号：EP1194139A1

  公开（公告）日：2002-04-10