dibutyltin(IV) bis(4-methoxyphenylethanoate) | 1161853-18-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: dibutyltin(IV) bis(4-methoxyphenylethanoate)
• CAS: 1161853-18-4
• 化学式: C₂₆H₃₆O₆Sn
• 分子量: 563.278
• InChiKey: KEBKHDSABNDXJQ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  二丁基二氯化锡 、 4-甲氧基苯乙酸钠盐 以 甲苯 为溶剂， 以79%的产率得到dibutyltin(IV) bis(4-methoxyphenylethanoate)
  参考文献：
  名称：

  Organotin(IV) 4-methoxyphenylethanoates: Synthesis, spectroscopic characterization, X-ray structures and in vitro anticancer activity against human prostate cell lines (PC-3)

  摘要：

  A series of organotin(IV) carboxylates, [Bu2SnL2] (1), [Et2SnL2] (2), [Me2SnL2] (3), [Bu3SnL](n) (4), [Me6Sn2L2](n) (5), [Ph3SnL](n) (6) and [Oct(2)SnL(2)] (7), where L = O2CCH2C6H4OCH3-4, have been synthesized. These complexes have been characterized by elemental analysis, FT-IR and multinuclear NMR (H-1, C-13 and Sn-119). Based on spectroscopic results, the ligand appeared to coordinate to the Sn atom through COO moiety. Single crystal analysis has shown a bridging behavior of ligand in tributyl- and trimethyl-tin(IV) derivatives, and a chelating bidentate mode in diethyltin(IV) complex. Bioassay results have shown that these compounds have good antibacterial, antifungal and antitumor activity. The activity against prostate cancer cell lines (PC-3) decreased in the order 1 > 5 > 2 > 3 > 7. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2009.01.003